Abstract
Alezzandrini syndrome (AS) is a rare entity characterized by segmental vitiligo on the face with ipsilateral poliosis, degenerative retinitis, and hearing defect on the same side. We hereby report a rare case of AS who presented to an ophthalmologist just for the treatment of his unilateral whitened eyebrows and eyelashes raising cosmetic concerns. Presence of ipsilateral vitiligo with pigmentary changes limited by midline over forehead aroused suspicion of shingles. However, careful, comprehensive examination and elicitation of some classical signs led to the coincidental diagnosis of the rare AS. Patient was explained possibility of visual deterioration and was advised regular follow up with an ophthalmologist. Hence, all cases of ipsilateral poliosis with segmental vitiligo should always be screened for retinal degeneration and hearing defects. Patients with AS should be managed by a team of ophthalmologists, dermatologists, and otorhinologists.