Abstracts of papers and posters advanced activities in pharmaceutical care 24th European Symposium on Clinical Pharmacy

第24届欧洲临床药学研讨会论文和海报摘要：药物治疗领域的先进活动

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作者：Hsieh,Cheng-Fang,Liu,Ching-Kuan,Fang,Tzu-Jung,Yu,Yau-Hua,Lai,Chiou-Lian,Kuo,Hsu-Ko,Nahata,M C,Bootman,J L,Zadák,Z,Soeters,P B,Goldberg,Laurence A,Stremetzne,S,Jaehde,U,Streit,M,Kreuser,E D,Thiel,E,Schunack,W,Calvert,R T,Feely,M,Chrystyn,H,Mangues,M A,Ginovart,G,Moral,M A,Lopes,A P,Farré,R,Demestre,X,Altirriba,O,Kloft,Ch,Beyer,J,Steuer,J,Siegert,W,Bever,J,Bialer,M,Sussan,S,Salach,O Abu,Danenberg,H D,Laor,A,Barnett,M I,Cosslett,A G,Cohen,J,Marini,P,Bassi,C,Bonzanini,A,Cassani,T,Dalle Ore,G,Mangiante,G,Scroccaro,G,Kaczan,M,Eriksen,J,Toft,B,Jandová,M,Vlček,J,Klemerová,V,Sobotka,L,Ayestarán,A,López,R,Montoro,J B,Pou,L,Estíbalez,A,Pascual,B,Aumente,M D,Panadero,M D,Caraballo,M,Pozo,J C,Perez,J L,Falcão,A C,Fernández de Gatta,M M,Dominguez-Gil,A,Caramona,M M,Lanao,J M,Fendrich,Z,Zajic,J,Bellés,Medall M D,Casabó,Alós V G,Jiménez,Torres N V,Hervás,Botella M A,Abad,Gimeno F J,Casterá,Melchor D E,Aminian,M,Mangues,M A,Clopés,A,Branco,C,Badell,I,Pardo,N,Palací,C,Bonal,J,Rialp,G,Bara,B,Nobilis,M,Bláha,V,Havel,E,Květina,J,Brátová,M,Solichová,D,Mullerova,M,Svoboda,D,Pokrajac,M,Miljković,B,Simić,D,Brzaković,B,Galetin,A,Pinheiro,R L,Carrondo,A P,Sieradzki,E,Strauss,K,Olejarz,E,Marzec,A,Kaużny,J,Szymura-Oleksiak,J,Wyska,E,Jarosz,B,Kosowicz,I,Fabirkiewicz,K,Cherian,R,Vodoz,A -L,Imsand,B,Belli,D,Rochat,Th,Müllerová,H,Falcão,F,Carvalho,A,Pereira,T,Fonseca,C,Freitas,O,Resende,M,Parrinha,A,Costa,M,Pessanha,M A,Ferreira,A,Mourão,L,Ceia,F,Lima,Mendonça,Tavares,R,SalesLuis,A,Carlos,Santos,Pereira,M E Araújo,Carmo,J Alves do,Lacerda,J M Forjaz,Morais,J A,Beaufils,C,Le Duff,M,Zamparutti,P,Assicot,P,Bohor,M,Angelini,B,Lambert,M,Manelli,J C,Gayte-Sorbier,A,Bongrand,M C,Timon-David,P,Fiqueira,I C,Lourenco,R,Silva,P A,Rodrigues,M O,Fischer,A,Schorr,W,Radziwill,R,Lihtamo,M,Jäppinen,A,Tuovinen,K,Pekkala,M,Nuutinen,L,Morató,L,Lorente,L,Muñoz,J,Monges,Ph,Blancard,A,Lacarelle,B,Denis,J P,Bongrand,M -C,Penot-Ragon,Ch,Gouin,F,Petitcollot,Nicole,Tinguely,I,Beney,J,Marty,S,Reymond,J -Ph,Bussels,J,Robays,H,Litzinger,A,Rohda-Bohler,R,Salek,M S,Turpin,S,Derby,E,Millar,B,Maggs,C,Santiago,L M,Batel,Marques,Cajaraville,G,Tarnés,M J,Díaz,M J,Del Pozo,C,Plazaola,A,Vuelta,M,Díaz-Munío,E,Ferrer,A,Lozano,A,Guerra,R,Pontón,J L,Robays,H,Kint,K,Verstraetep,A,Eini,D El,Ojala,R K,Kontra,K M,Naaranlahti,T J P,Martorell,M,Oliveras,M,Juste,C,Lopez,M T,Hidalgo,E,Cabañas,M J,Barroso,C,Llop,J M,Rey,M,Diaz-Munio,E,Pastó,L,Tubau,M,Gómez-Bellver,M J,Rodriguez,J,Gómez,J M,Gónzalez,M L,Gol,V,Fuentes,V,Ramón,S,Girona,L,Castelló,T,Olona,M,García,L,Girón,C,Monteserín,C,Gonzalez,P,Alberola,C,Feio,J A L,Pharm,D,Batel Marques,F J,Borges,Alexandrino M,Salek,S,Escoms,M C,Caro,I,Ticó,N,Hidalgo,M,Bruguera,R,Jodar,R,Dowell,J M,Davey,P G,Malek,M,Díaz-Munío,E,Vuelta,M,Pastó,L,Rev,M,Ferrer,I,Llop,J M,Marti,T,Ibars,M,Delporte,J P,Ansseau,M,Albert,A,Sibourg,M,Gaspard,O,Deprez,M,Ndougsa,H M,Poma,M,Tamés,M J,Macek,K,Vlček,J,Fendrich,Z,Klejna,M,Dhillon,S,Castro,I,Newton,M,Zupanets,I A,Chernyh,V P,Bezdetko,N B,Popov,S B,Velieva,M N,Babajeya,S M,Mamedov,Y D,Mammedov,Y Dj,Veliev,P M,Nasudari,A A,Bandalieva,A A,Nordbo,S,Smith-Solbakken,M,Myklctun,R,Berge,W,Thormodsen,M,Zupanets,L A,Kicenko,L S,Plusch,S I,Isaev,S G,Vokrouhlický,L,Souček,R,Kuneš,P,Nývlt,O,Potselueva,L A,Egorova,S N,Kadirova,E A,Ziganshina,L E,Chaloupka,J,Genger,K
期刊：影响因子：
时间：1995起止号：1995;17(10):J7-J28
doi：10.1093/gerona/glp081

Abstract

BACKGROUND: Patients with chronic viral hepatitis are at a higher risk for cognitive dysfunction. Little is known about the association between hepatitis A virus (HAV) infection and cognitive function. METHODS: From the National Health and Nutrition Examination Survey, 1999-2002, we selected study participants (> or =60 years, n = 1,529) without hepatitis B, C, or D virus infection; without previous hepatitis A vaccination; and without abnormal liver function. HAV-seropositive participants represented people with previous HAV infection. Psychomotor speed and executive functioning domain of cognitive function were measured by the Digit Symbol Substitution Test (DSST). RESULTS: HAV-seropositive participants had lower DSST scores than HAV-seronegative participants (weighted mean, 44.4 vs 53.9, p < .001). We designated HAV-seronegative participants as the reference group. Univariate analysis demonstrated that the weighted beta coefficient of DSST score was -9.55 (95% confidence interval [CI] -9.57 to -9.54, p < .001) for the HAV-seropositive participants. In a multivariable model, the weighted adjusted beta coefficient of DSST score was -2.48 (95% CI -2.49 to -2.46, p < .001) for the HAV-seropositive participants. CONCLUSION: HAV seropositivity is associated with slower psychomotor speed among the U.S. community-dwelling elders.

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