Abstract
BACKGROUND: Currently, there is a scarcity of research exploring the connection between work schedules and coronary heart disease (CHD) or angina. Previous studies on the associations between work schedules and CHD or angina have been primarily limited to specific occupations, particular genders, small sample sizes, or narrow regional focus. This study aims to evaluate the potential association between work schedules and CHD or angina among adults in the United States. METHODS: In this cross-sectional study, we selected 13,147 adults aged ≥ 20 years from the National Health and Nutrition Examination Survey 2005-2010 and 2017-2020 cycles. We computed adjusted odds ratio (OR) and 95 % confidence interval (CI) utilizing multivariate logistic regression models. Meticulous subgroup analyses were conducted to ensure the reliability and consistency of our findings. Propensity score assessments were implemented to enhance the comparability between daytime workers and evening or night workers, thereby facilitating a more accurate estimation. RESULTS: Among the participants, 216 were diagnosed with CHD, while 125 were diagnosed with angina. Evening or night workers exhibited a prevalence of CHD that was 1.87 times higher than that of daytime workers (OR: 1.87, 95 % CI: 1.19-2.95, P = 0.007). Furthermore, evening or night workers exhibited a prevalence of angina that was 1.81 times higher than that of daytime workers (OR: 1.81, 95 % CI: 1.05-3.12, P = 0.033). Our findings demonstrated robustness and reliability through subgroup analyses and propensity score assessments. CONCLUSIONS: In conclusion, evening or night work schedules were associated with increased CHD and angina risk. Further research should explore biological mechanisms for prevention in this population.