Intradural calcifying pseudoneoplasm of the neuraxis in the lumbosacral canal: Two case reports and review of the literature

腰骶管神经轴硬膜内钙化性假瘤:两例病例报告及文献复习

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Abstract

BACKGROUND: Calcifying pseudoneoplasms of the neuraxis (CAPNON) are benign and slowly growing fibro-osseous lesions of the nervous system. METHODS: We report two rare cases of spinal CAPNON and provide a literature review. RESULTS: A 33-year-old woman with back pain underwent lumbar magnetic resonance imaging (MRI), revealing a large intradural mass (1.5 × 0.9 × 10.6cm(3)) at L2-S1. Postoperative MRI scan performed 3 years after surgery confirmed no recurrence. A 64-year-old woman with lower limb numbness and gait instability underwent lumbar MRI, revealing an L3 intradural mass (1.1 × 0.3 × 1.6cm(3)). Lower limb numbness were resolved after surgery during 1 year follow-up. CONCLUSION: Accurate recognition of CAPNON is essential to guide appropriate surgical intervention due to its favorable prognosis. In these situations, complete resection and radiological follow-up are highly recommended.

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