The effectiveness of an immersive virtual reality and telemedicine-based cognitive intervention on prospective memory in Parkinson's disease patients with mild cognitive impairment and healthy aged individuals: design and preliminary baseline results of a placebo-controlled study

沉浸式虚拟现实和远程医疗认知干预对轻度认知障碍的帕金森病患者和健康老年人前瞻性记忆的有效性:安慰剂对照研究的设计和初步基线结果

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作者:Maria Stefania De Simone, Alberto Costa, Gaetano Tieri, Sara Taglieri, Giorgia Cona, Eleonora Fiorenzato, Giovanni Augusto Carlesimo, Carlo Caltagirone, Silvia Zabberoni

Conclusion

Considering the relatively low costs and easy accessibility to this program, it could prove valuable in primary prevention initiatives and early cognitive rehabilitation for dementia risk reduction.

Methods

Outcome measures, collected before, immediately after and 2 months after the intervention, included: (1) pre-post training changes in objective cognitive functioning, evaluated with tests assessing executive functions and PM; (2) pre-post training changes in subjective perception of memory functioning, psychiatric symptoms, autonomy in daily living and quality of life, evaluated using the appropriate scales; (3) usability, feasibility and users' compliance with the proposed IVR and telemedicine program. The efficacy of this intervention compared to an active control condition is currently being evaluated in a randomized, double-blind controlled trial, which will be conducted on 30 eligible PD-MCI patients and 30 older adults.

Objective

Here, we aimed to present the study protocol and preliminary

Results

Preliminary results concerning between-group comparisons of demographic and neuropsychological screening data show a good balance among the intervention groups considered in this study. The results also suggest good levels of usability, feasibility and acceptability, thus supporting the notion that our intervention can be used to promote cognitive functioning, even in people with cognitive decline.

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