Two cases of childhood linear immunoglobulin A bullous dermatosis following multivisceral transplant: A case report

两例儿童多脏器移植后发生线性免疫球蛋白A大疱性皮肤病:病例报告

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Abstract

Childhood linear immunoglobulin A bullous dermatosis is a well-recognized autoimmune blistering dermatosis that can be idiopathic, drug-induced, secondary to autoimmune diseases, malignancies, infections, or gastrointestinal diseases including inflammatory bowel disease. However, it has not been previously associated with a history of organ transplantation. Here, we report two cases of childhood linear immunoglobulin A bullous dermatosis in young infants following multivisceral organ transplant, including one with a particularly recalcitrant course. We propose potential mechanisms contributing to the development of linear immunoglobulin A bullous dermatosis and challenges in the management of these patients in light of their complex medical histories and immunosuppression.

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