Ultrasensitive and Highly Selective Electrochemical Detection of Dopamine Using Poly(ionic liquids)-Cobalt Polyoxometalate/CNT Composite

利用聚离子液体-钴多金属氧酸盐/碳纳米管复合材料实现多巴胺的超灵敏高选择性电化学检测

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Abstract

A novel sandwich polyoxometalate (POM) Na(12)[WCo(3)(H(2)O)(2)(CoW(9)O(34))(2)] and poly(vinylimidazolium) cation [PVIM(+)] in combination with nitrogen-doped carbon nanotubes (NCNTs) was developed for a highly selective and ultrasensitive detection of dopamine. Conductively efficient heterogenization of Co(5)POM catalyst by PVIM over NCNTs provides the synergy between PVIM-POM catalyst and NCNTs as a conductive support which enhances the electron transport at the electrode/electrolyte interface and eliminates the interference of ascorbic acid (AA) at physiological pH (7.4). The novel PVIM-Co(5)POM/NCNT composite demonstrates a superior selectivity and sensitivity with a lowest detection limit of 500 pM (0.0005 μM) and a wide linear detection range of 0.0005-600 μM even in the presence of higher concentration of AA (500 μM).

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