Proximal Junction and Transitional Mechanics and Effect of a Novel Tether Pedicle Screw in Long-Segment Spinal Instrumentation

近端连接和过渡力学以及新型系绳椎弓根螺钉在长节段脊柱内固定术中的作用

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Abstract

STUDY DESIGN: A biomechanical study of 10 human thoracolumbar (T7-L2) spine specimens was performed. OBJECTIVE: To analyze the biomechanical characteristics of a Tether pedicle screw (TPS) in long-segment thoracolumbar instrumentation in terms of proximal junction mechanics and transitional motion patterns. BACKGROUND: Adult spinal deformity correction carries a high junctional failure risk. A soft-landing construct at a rigid construct cranial end might reduce the proximal junctional kyphosis and proximal junctional failure risks. Therefore, a novel TPS was designed to mitigate the proximal junctional kyphosis/proximal junctional failure risk. The pedicle screw is characterized by a tether between the threaded shaft and the screw head, enabling motion among parts. MATERIALS AND METHODS: For initial flexibility tests, 3 instrumentation patterns were tested. Representing conventional instrumentation, standard thoracolumbar pedicle screw-rod instrumentation at T10 to L2 was used [standard (STD) group]. The TPS was tested at T9 (TPS+1 group), 1 level above the upper instrumented vertebra, and at T9 and T8 (TPS+2 group). Flexibility tests (±5 Nm) in all 3 motion directions were performed and repeated after cyclic loading (250 cycles, 1-10 Nm). Finally, specimens in the STD and TPS groups were subjected to screw pull-out testing at the index level to analyze the TPS stress-shielding effects. RESULTS: The TPS+2 group demonstrated the largest range of motion decrease at T9 to T10 in the flexibility tests, with a smaller effect in the second adjacent segment at T8 to T9. No significant change in range of motion was observed in the uppermost segment (T7-T8) among all instrumentation pattern studies. Pull-out testing revealed greater mean forces at the T10 end-level in the TPS+2 group than in the STD group. CONCLUSION: The TPS effectively distributed the loads across 3 adjacent levels and softened the load transition compared with the rigid construct. The TPS also showed the potential to stress-shield the upper instrumented vertebra (T10) and reduce the end-level screw loosening risk.

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