Abstract
Multiple scattering in turbid media inhibits optimal light focusing and thus limits the penetration depth in optical coherence tomography (OCT). However, the effects of multiple scattering in a turbid medium can be systematically controlled by shaping the incident wavefront. The authors utilize the reciprocity of Maxwell's equations and finite-difference time-domain numerical analysis to investigate the ultimate performance bounds of wavefront shaping-OCT under ideal and realistic configurations and compare them with the conventional method. The results reveal that the optimized impinging wavefront significantly enhances the penetration depth of OCT.