Successful Repeated Use of a Pathogen Adsorbing Biomimetic Device for the Adjunct Treatment of a SARS-CoV-2 Reinfection and Subsequent Infections with Different Multiresistant Bacteria

成功重复使用病原体吸附仿生装置辅助治疗SARS-CoV-2再感染及随后发生的多种耐药菌感染

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Abstract

INTRODUCTION: The Seraph(®) 100 Microbind(®) Affinity Filter is a biomimetic adsorbent device that can remove pathogens from the blood. CASE PRESENTATION: Here, we report the successful use of the Seraph(®) 100 to treat both a SARS-CoV-2 reinfection leading to severe COVID-19 pneumonia as well as subsequent secondary lung infections including Acinetobacter baumannii, Serratia marcescens, and Pseudomonas aeruginosa multidrug-resistant bacteria. To our knowledge, this 46-year-old black male is the first patient in which four treatments with this pathogen adsorber, one for a viral and three for different bacterial infections, have been successfully used. CONCLUSION: The Seraph(®) 100 can be easily and successfully used in conjunction with standard (anti-infective) treatment.

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