Abstract
We are reporting a rare case of hemolytic disease of newborn with weak D antigen in child. A 3(rd) order male child of G(3)P(3)A(0) mother was admitted at 8(th) h of life with jaundice. Blood group of both mother and child were A Rh D negative. Baby's direct coombs test was positive. Weak D antigen was positive in baby. Hematological parameters showed all the signs of ongoing hemolysis, and the bilirubin level was in the zone of exchange transfusion. Exchange transfusion was done. An intravenous immunoglobulin was given to child after that. Mother had a history of first normal healthy male child with O Rh D positive blood group. Second male child expired on 3(rd) postnatal day due to bilirubin encephalopathy that had A Rh D negative blood group with positive direct coombs test.