Imlunestrant Is an Oral, Brain-Penetrant Selective Estrogen Receptor Degrader with Potent Antitumor Activity in ESR1 Wild-Type and Mutant Breast Cancer
Imlunestrant 是一种口服、脑渗透性选择性雌激素受体降解剂，对 ESR1 野生型和突变型乳腺癌具有强效抗肿瘤活性
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作者：Shripad V Bhagwat #, Cecilia Mur #, Matthew Vandekopple #, Baohui Zhao, Weihua Shen, Carlos Marugán, Andrew Capen, Lisa Kindler, Jennifer R Stephens, Lysiane Huber, Mark A Castanares, David Garcia-Tapia, Jeff D Cohen, Jolie Bastian, Brian Mattioni, Eunice Yuen, Thomas K Baker, Vivian Rodriguez Cruz,
| 期刊： | Cancer Research | 影响因子： | 12.500 |
| 时间： | 2025 | 起止号： | 2025 Feb 17;85(4):777-790. |
| doi： | 10.1158/0008-5472.CAN-24-2608 | 研究方向： | 肿瘤 |
| 疾病类型： | 乳腺癌 | |
