Abstract
Antimicrobial properties of plants have been investigated by a number of studies worldwide and many of them have been used as therapeutic alternatives because of their antimicrobial properties. The quest for suitable and affordable alternative in the face of increasing antimicrobial drug resistant has led researchers into exploring the use of plant extract in the treatment of infections. The antibacterial properties of turmeric (Curcuma longa) on selected bacteria were evaluated. Different concentrations of turmeric extract (100, 50, 25, and 12.5 mg/mL) were prepared using 2 solvents namely water and ethanol. The antibacterial activity was tested against Bacillus species, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa at different concentration of the extract using disc diffusion method and ciprofloxacin was the control. The zones of inhibition exhibited by ethanol and aqueous extracts against test organisms ranged from 1 to 10 mm. the ethanolic extracts were more effective than the aqueous extracts exhibiting zones of inhibition ranging from 3 to 10 mm against Bacillus species, 4 to 9 mm against S aureus, and 1 to 7 mm against E coli. There was no inhibitory effect against P aeruginosa. There was significant difference between the ethanol and aqueous extracts (P < .05). This study reveal that Turmeric plant has antibacterial potential against selected organisms and may be of great use of pharmaceutical industries for the development of medicine to cure ailments and control abnormal serum lipid profile.