Phenotypic and genomic analysis of bacteria from war wounds in Dnipro, Ukraine

对乌克兰第聂伯罗战争伤口中细菌的表型和基因组分析

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Abstract

OBJECTIVES: To better understand the source and potential transmission routes of antibiotic-resistant bacteria infecting injured service members in Ukraine. METHODS: Phenotypic and genomic characterizations were performed on 11 Gram-negative pathogens cultured from war wounds at an intermediate evacuation hospital in Dnipro. RESULTS: The analysis revealed both susceptible and extensively drug-resistant strains present in cultures, including high-risk global clones carrying carbapenemases. CONCLUSIONS: Globally distributed carbapenemase-producing lineages are being acquired early in the medical evacuation process.

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