Controlled oligomerization of [1.1.1]propellane through radical polarity matching: selective synthesis of SF(5)- and CF(3)SF(4)-containing [2]staffanes

通过自由基极性匹配控制[1.1.1]丙烷的低聚:选择性合成含SF(5)和CF(3)SF(4)的[2]斯塔法烷

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Abstract

Selectivity in radical chain oligomerizations involving [1.1.1]propellane - i.e., to make [n]staffanes - has been notoriously challenging to control when n > 1 is desired. Herein, we report selective syntheses of SF(5)- and CF(3)SF(4)-containing [2]staffanes from SF(5)Cl and CF(3)SF(4)Cl, demonstrating cases whereby oligomerization is preferentially truncated after incorporation of two bicyclopentane (BCP) units. Synthetic and computational studies suggest this phenomenon can be attributed to alternating radical polarity matching. In addition, single-crystal X-ray diffraction (SC-XRD) data reveal structurally interesting features of the CF(3)SF(4)-containing [2]staffane in the solid state.

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