Abstract
Tribolium castaneum Herbst is a destructive stored product pest. The aggregation pheromone of this pest was prepared via a new and effective strategy. The key steps include the ring-opening reaction of chiral 2-methyloxirane, the stereospecific inversion of chiral secondary tosylate, Li(2)CuCl(4)-catalyzed coupling of tosylate with Grignard reagent, and oxidation with RuCl(3)/NaIO(4.)