DNA sensors with diamond as a promising alternative transducer material

以金刚石作为有前途的替代传感器材料的DNA传感器

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作者:Veronique Vermeeren, Sylvia Wenmackers, Patrick Wagner, Luc Michiels

Abstract

Bio-electronics is a scientific field coupling the achievements in biology with electronics to obtain higher sensitivity, specificity and speed. Biosensors have played a pivotal role, and many have become established in the clinical and scientific world. They need to be sensitive, specific, fast and cheap. Electrochemical biosensors are most frequently cited in literature, often in the context of DNA sensing and mutation analysis. However, many popular electrochemical transduction materials, such as silicon, are susceptible to hydrolysis, leading to loss of bioreceptor molecules from the surface. Hence, increased attention has been shifted towards diamond, which surpasses silicon on many levels.

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