Odorranalectin is a small peptide lectin with potential for drug delivery and targeting

Odorranalectin 是一种小肽凝集素,具有药物输送和靶向潜力

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作者:Jianxu Li, Hongbing Wu, Jing Hong, Xueqing Xu, Hailong Yang, Bingxian Wu, Yipeng Wang, Jianhua Zhu, Ren Lai, Xinguo Jiang, Donghai Lin, Mark C Prescott, Huw H Rees

Background

Lectins are sugar-binding proteins that specifically recognize sugar complexes. Based on the specificity of protein-sugar interactions, different lectins could be used as carrier molecules to target drugs specifically to different cells which express different glycan arrays. In spite of lectin's interesting biological potential for drug targeting and delivery, a potential disadvantage of natural lectins may be large size molecules that

Conclusion

These findings identify the smallest lectin so far, and show the application potential of odorranalectin for drug delivery and targeting. It also disclosed a new strategy of amphibian anti-infection.

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