Dietary Bacillus licheniformis improves the effect of Astragalus membranaceus extract on blood glucose by regulating antioxidation activity and intestinal microbiota in InR[E19]/TM2 Drosophila melanogaster

膳食地衣芽孢杆菌通过调节 InR[E19]/TM2 果蝇的抗氧化活性和肠道菌群来改善黄芪提取物对血糖的影响

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作者:Denghui Wang, Yaxin Zhang, Meiling Xu, Xiaoling Sun, Xiulin Cui, Xiuran Wang, Dongbo Liu

Background

The diabetes mellitus prevalence is rapidly increasing in most parts of the world and has become a vital health problem. Probiotic and herbal foods are valuable in the treatment of diabetes.

Conclusion

The obtained results showed that dietary supplementation with BL and AE, under the synergistic effect of BL and AE, not only prolonged the lifespan of InR[E19]/TM2 D. melanogaster, increased body weight, and improved the body's antiaging enzyme activity but also effectively improved the types and quantities of beneficial bacteria in the intestinal flora of InR[E19]/TM2 D. melanogaster to improve the characteristics of diabetes symptoms. This study provides scientific evidence for a safe and effective dietary therapeutic method for diabetes mellitus.

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