A portable system for processing donated whole blood into high quality components without centrifugation

一种无需离心即可将捐献的全血处理成高质量成分的便携式系统

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作者:Sean C Gifford, Briony C Strachan, Hui Xia, Eszter Vörös, Kian Torabian, Taylor A Tomasino, Gary D Griffin, Benjamin Lichtiger, Fleur M Aung, Sergey S Shevkoplyas

Background

The use of centrifugation-based approaches for processing donated blood into components is routine in the industrialized world, as disparate storage conditions require the rapid separation of 'whole blood' into distinct red blood cell (RBC), platelet, and plasma products. However, the logistical complications and potential cellular damage associated with centrifugation/apheresis manufacturing of blood products are well documented. The

Conclusion

This study demonstrated that a simple, passive system for separating donated blood into components may be a viable alternative to centrifugation-particularly for applications in remote or resource-limited settings, or for patients requiring highly functional platelet product.

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