Evaluation of chemopreventive effects of Acanthus ilicifolius against azoxymethane-induced aberrant Crypt Foci in the rat colon

评价老鼠簕对氧化偶氮甲烷诱发的大鼠结肠异常隐窝灶的化学预防作用

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作者:Amel A Almagrami, Mohammed A Alshawsh, Riyadh Saif-Ali, Abdrabuh Shwter, Sameer D Salem, Mahmood A Abdulla

Background

Acanthus ilicifolius, a mangrove medicinal plant, is traditionally used to treat a variety of diseases. The

Significance

The results of the current study show that AOM-treated rats receiving oral exposure to A. ilicifolius demonstrated a significant decrease in the number of ACF in the colon when compared to AOM-treated rats receiving vehicle only. A ilicifolius may be an effective herbal approach for the prevention of AOM-induced ACF in the rat colon.

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