Comparative In Vivo Effects of Hemoglobin-Based Oxygen Carriers (HBOC) with Varying Prooxidant and Physiological Reactivity
具有不同促氧化剂和生理反应性的血红蛋白氧载体 (HBOC) 的体内效应比较
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作者：Vlad Al Toma, Anca D Farcaș, Ioana Roman, Bogdan Sevastre, Denisa Hathazi, Florina Scurtu, Grigore Damian, Radu Silaghi-Dumitrescu
| 期刊： | PLoS One | 影响因子： | 2.900 |
| 时间： | 2016 | 起止号： | 2016 Apr 20;11(4):e0153909. |
| doi： | 10.1371/journal.pone.0153909 |
Abstract
A series of hemoglobin-based oxygen carrier candidates (HBOC), previously noted for their differences in prooxidative and physiological reactivity, were compared in terms of the negative effects displayed upon injection in Wistar rats. At the concentrations tested, antioxidant strategies based on albumin as well as based on rubrerythrin appear to offer observable physiological advantages.
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