Global analysis of circulating immune cells by matrix-assisted laser desorption ionization time-of-flight mass spectrometry

MALDI-TOF mass spectrometry is currently used in microbiological diagnosis to characterize bacterial populations. Our

This method was rapid and easy to perform, and unlike flow cytometry, it did not require any additional components such as specific antibodies. The MALDI-TOF mass spectrometry approach could be extended to analyze the cell composition of tissues and the activation state of immune cells.