Water-soluble extract of Pacific Krill prevents triglyceride accumulation in adipocytes by suppressing PPARγ and C/EBPα expression

太平洋磷虾的水溶性提取物通过抑制 PPARγ 和 C/EBPα 表达来防止脂肪细胞中甘油三酯的积累

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作者:Hidetoshi Yamada, Tomohiro Ueda, Akira Yano

Background

Pacific Krill (Euphausia pacifica) are small, red crustaceans, similar to shrimp, that flourish in the North Pacific and are eaten in Japan.

Conclusions

These results indicated that the water-soluble extract of Pacific Krill was not simply a PPARγ antagonist, but that it prevented triglyceride accumulation in adipocytes by suppression of PPARγ and C/EBPα via a pathway that is independent of C/EBPβ.

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