Infusion of megakaryocytic progenitor products generated from cord blood hematopoietic stem/progenitor cells: results of the phase 1 study

输注脐带血造血干细胞/祖细胞产生的巨核细胞祖细胞产品:第一阶段研究的结果

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作者:Jiafei Xi, Honghu Zhu, Daqing Liu, Xue Nan, Wen Zheng, Kaiyan Liu, Wei Shi, Lin Chen, Yang Lv, Fang Yan, Yanhua Li, Xiaoyan Xie, Yunfang Wang, Wen Yue, Xin Xu, Xiaofei Wei, Jun Zhu, Xiaojun Huang, Xuetao Pei

Background

Currently, a constant shortage in the supply of platelets has become an important medical and society challenge, especially in developing country, and the in vitro production of megakaryocytic progenitor cells (MPs) from cord blood could represent an effective platelet substitute. In the present study, our

Conclusions

These initial results in patients are very encouraging. They suggest that infusion of cord blood-derived MPs appears safe and feasible for treatment of thrombocytopenia.

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