日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of BI-2493, a Pan-KRAS Inhibitor Showing In Vivo Efficacy.

发现 BI-2493，一种泛 KRAS 抑制剂，显示出体内疗效

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00576
Bröker Joachim, Waterson Alex G, Hodges Timothy R, Abbott Jason R, Arnold Allison, Böttcher Jark, Braun Nina, Cui Jianwen, Fuchs Julian E, Gerstberger Thomas, Gogg Sebastian, Hanner Sabine, Herdeis Lorenz, Howell Lucas W, Mantoulidis Andreas, Mayer Moriz, Phan Jason, Rocchetti Francesca, Sankar Kyra, Sarkar Dhruba, Schaaf Otmar, Sensintaffar John L, Sun Qi, Wunberg Tobias, Fesik Stephen W
其它
发表日期：2025
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Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS

苯并咪唑衍生物激活剂对 RAS 上 SOS1 介导的核苷酸交换的发现和基于结构的优化

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.8b01108
Hodges, Timothy R; Abbott, Jason R; Little, Andrew J; Sarkar, Dhruba; Salovich, James M; Howes, Jennifer E; Akan, Denis T; Sai, Jiqing; Arnold, Allison L; Browning, Carrie; Burns, Michael C; Sobolik, Tammy; Sun, Qi; Beesetty, Yugandhar; Coker, Jesse A; Scharn, Dirk; Stadtmueller, Heinz; Rossanese, Olivia W; Phan, Jason; Waterson, Alex G; McConnell, Darryl B; Fesik, Stephen W
RAS
发表日期：2018
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Stereoselective synthesis of the disaccharide unit of incednine

因西丁二糖单元的立体选择性合成

期刊:Organic Letters
影响因子:5
doi:10.1021/ol303093z
Abbott, Jason R; Roush, William R
发表日期：2013
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Stereoselective synthesis of a model C(18)-C(35) spiroketal fragment of integramycin

整合霉素模型C(18)-C(35)螺缩酮片段的立体选择性合成

期刊:Organic Letters
影响因子:5
doi:10.1021/ol200834p
Sun, Huikai; Abbott, Jason R; Roush, William R
发表日期：2011
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