Abouzayed相关文献与解析，生知库 | 链接生命科学的每一步

Abouzayed, Ayman; Olsson, Hugo; Papadopoulos, Natalia; Mitran, Bogdan; Mallapura, Hemantha; Akter, Tahmida; Velikyan, Irina; Korsgren, Olle; Heldin, Carl-Henrik; Löfblom, John; Wagner, Michael; Eriksson, Olof

发表日期：2026

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Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [(99m)Tc]Tc-labeled counterparts be used to estimate dosimetry?

评估用 Re-188 标记的 maSSS/maSES-PEG2-RM26 的潜在治疗用途。能否使用其 [(99m)Tc]Tc 标记的对应物来估计剂量学？

期刊:EJNMMI Radiopharmacy and Chemistry

影响因子:3.3

doi:10.1186/s41181-024-00326-3

Kanellopoulos, Panagiotis; Yu, Quanyi; Abouzayed, Abouzayed; Bezverkhniaia, Ekaterina; Tolmachev, Vladimir; Orlova, Anna

发表日期：2025

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Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [(18)F]MeTz-PEG(2)-RM26 for positron emission tomography

合成及胃泌素释放肽受体拮抗剂[(18)F]MeTz-PEG(2)-RM26用于正电子发射断层扫描的临床前评价

期刊:EJNMMI Radiopharmacy and Chemistry

影响因子:3.3

doi:10.1186/s41181-025-00336-9

Kanellopoulos, Panagiotis; Lundmark, Fanny; Abouzayed, Ayman; Balestri, Lorenzo Jacopo Ilic; Håkansson, Esther Olaniran; Obeid, Karim; Odell, Luke R; Tolmachev, Vladimir; Rosenström, Ulrika; Eriksson, Jonas; Orlova, Anna

信号转导

发表日期：2025

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PDGFRÃ targeted positron emission tomography as a non-invasive biomarker for activated hepatic stellate cells: lasts steps before clinical translation.

PDGFRÃŸ靶向正电子发射断层扫描作为活化肝星状细胞的非侵入性生物标志物：临床转化前的最后步骤。

期刊:EJNMMI Radiopharmacy and Chemistry

影响因子:3.3

doi:10.1186/s41181-025-00410-2

Yashaswini Chittampalli N, Mitran Bogdan, Papadopoulos Natalia, Wegrzyniak Olivia, LÃ¶fblom John, NordstrÃ¶m Helena, Velikyan Irina, Abouzayed Ayman, Johansson Lars, Hagmar Per, Wagner Michael, Frejd Fredrik Y, Korsgren Olle, Heldin Carl-Henrik, Friedman Scott L, Eriksson Olof

细胞生物学

发表日期：2025

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GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics

通过带正电荷的连接子携带 DOTAGA 螯合剂的 GRPR 拮抗剂：前列腺癌诊疗一体化的前景

期刊:Pharmaceutics

影响因子:5.5

doi:10.3390/pharmaceutics16040513

Obeid, Karim; Kanellopoulos, Panagiotis; Abouzayed, Ayman; Mattsson, Adam; Tolmachev, Vladimir; Nock, Berthold A; Maina, Theodosia; Orlova, Anna

Two Novel [(68)Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar(11)]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

两种基于代谢稳定的[Sar(11)]RM26拮抗肽的新型[(68)Ga]Ga标记放射性示踪剂用于GRPR阳性前列腺癌的诊断性正电子发射断层扫描成像

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.4c01348

Kanellopoulos, Panagiotis; Bezverkhniaia, Ekaterina; Abouzayed, Ayman; Rosenström, Ulrika; Tolmachev, Vladimir; Orlova, Anna

Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery

评估 ABD 连接的 RM26 结合物对 GRPR 靶向药物输送的作用

期刊:ACS Omega

影响因子:3.7

doi:10.1021/acsomega.4c00489

Ábel Nagy, Ayman Abouzayed, Panagiotis Kanellopoulos, Fredrika Landmark, Ekaterina Bezverkhniaia, Vladimir Tolmachev, Anna Orlova, Amelie Eriksson Karlström

发表日期：2024

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Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

靶向人表皮生长因子受体-3的亲和体-药物偶联物在携带低表达异种移植瘤的小鼠中显示出治疗效果

期刊:ACS Pharmacology and Translational Science

影响因子:3.7

doi:10.1021/acsptsci.4c00402

Zhang, Jie; Rinne, Sara S; Yin, Wen; Leitao, Charles Dahlsson; Björklund, Elvira; Abouzayed, Ayman; Ståhl, Stefan; Löfblom, John; Orlova, Anna; Gräslund, Torbjörn; Vorobyeva, Anzhelika

Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology

对具有更高代谢稳定性的新型GRPR拮抗剂进行临床前评估，用于肿瘤放射治疗诊断

期刊:EJNMMI Radiopharmacy and Chemistry

影响因子:3.3

doi:10.1186/s41181-024-00242-6

Kanellopoulos, Panagiotis; Mattsson, Adam; Abouzayed, Ayman; Obeid, Karim; Nock, Berthold A; Tolmachev, Vladimir; Maina, Theodosia; Orlova, Anna

Preclinical Characterization of a Stabilized Gastrin-Releasing Peptide Receptor Antagonist for Targeted Cancer Theranostics

用于靶向癌症诊疗的稳定型胃泌素释放肽受体拮抗剂的临床前表征

期刊:Biomolecules

影响因子:4.8

doi:10.3390/biom13071134

Abouzayed, Ayman; Kanellopoulos, Panagiotis; Gorislav, Alisa; Tolmachev, Vladimir; Maina, Theodosia; Nock, Berthold A; Orlova, Anna

Increased affinity by dimerization of radiolabeled Affibody molecule ATH001 targeting PDGFRβ

放射性标记的Affibody分子ATH001通过二聚化作用增强其对PDGFRβ的亲和力

Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [(99m)Tc]Tc-labeled counterparts be used to estimate dosimetry?

评估用 Re-188 标记的 maSSS/maSES-PEG2-RM26 的潜在治疗用途。能否使用其 [(99m)Tc]Tc 标记的对应物来估计剂量学？

Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [(18)F]MeTz-PEG(2)-RM26 for positron emission tomography

合成及胃泌素释放肽受体拮抗剂[(18)F]MeTz-PEG(2)-RM26用于正电子发射断层扫描的临床前评价

PDGFRÃ targeted positron emission tomography as a non-invasive biomarker for activated hepatic stellate cells: lasts steps before clinical translation.

PDGFRÃŸ靶向正电子发射断层扫描作为活化肝星状细胞的非侵入性生物标志物：临床转化前的最后步骤。

GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics

通过带正电荷的连接子携带 DOTAGA 螯合剂的 GRPR 拮抗剂：前列腺癌诊疗一体化的前景

Two Novel [(68)Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar(11)]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

两种基于代谢稳定的[Sar(11)]RM26拮抗肽的新型[(68)Ga]Ga标记放射性示踪剂用于GRPR阳性前列腺癌的诊断性正电子发射断层扫描成像

Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery

评估 ABD 连接的 RM26 结合物对 GRPR 靶向药物输送的作用

Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

靶向人表皮生长因子受体-3的亲和体-药物偶联物在携带低表达异种移植瘤的小鼠中显示出治疗效果

Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology

对具有更高代谢稳定性的新型GRPR拮抗剂进行临床前评估，用于肿瘤放射治疗诊断

Preclinical Characterization of a Stabilized Gastrin-Releasing Peptide Receptor Antagonist for Targeted Cancer Theranostics

用于靶向癌症诊疗的稳定型胃泌素释放肽受体拮抗剂的临床前表征

Increased affinity by dimerization of radiolabeled Affibody molecule ATH001 targeting PDGFRβ

放射性标记的Affibody分子ATH001通过二聚化作用增强其对PDGFRβ的亲和力

Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [(99m)Tc]Tc-labeled counterparts be used to estimate dosimetry?

评估用 Re-188 标记的 maSSS/maSES-PEG2-RM26 的潜在治疗用途。能否使用其 [(99m)Tc]Tc 标记的对应物来估计剂量学？

Synthesis and preclinical evaluation of gastrin releasing peptide receptor antagonist [(18)F]MeTz-PEG(2)-RM26 for positron emission tomography

合成及胃泌素释放肽受体拮抗剂[(18)F]MeTz-PEG(2)-RM26用于正电子发射断层扫描的临床前评价

PDGFRÃ targeted positron emission tomography as a non-invasive biomarker for activated hepatic stellate cells: lasts steps before clinical translation.

PDGFRÃŸ靶向正电子发射断层扫描作为活化肝星状细胞的非侵入性生物标志物：临床转化前的最后步骤。

GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics

通过带正电荷的连接子携带 DOTAGA 螯合剂的 GRPR 拮抗剂：前列腺癌诊疗一体化的前景

Two Novel [(68)Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar(11)]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer

两种基于代谢稳定的[Sar(11)]RM26拮抗肽的新型[(68)Ga]Ga标记放射性示踪剂用于GRPR阳性前列腺癌的诊断性正电子发射断层扫描成像

Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery

评估 ABD 连接的 RM26 结合物对 GRPR 靶向药物输送的作用

Affibody-Drug Conjugates Targeting the Human Epidermal Growth Factor Receptor-3 Demonstrate Therapeutic Efficacy in Mice Bearing Low Expressing Xenografts

靶向人表皮生长因子受体-3的亲和体-药物偶联物在携带低表达异种移植瘤的小鼠中显示出治疗效果

Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology

对具有更高代谢稳定性的新型GRPR拮抗剂进行临床前评估，用于肿瘤放射治疗诊断

Preclinical Characterization of a Stabilized Gastrin-Releasing Peptide Receptor Antagonist for Targeted Cancer Theranostics

用于靶向癌症诊疗的稳定型胃泌素释放肽受体拮抗剂的临床前表征

PDGFRÃ targeted positron emission tomography as a non-invasive biomarker for activated hepatic stellate cells: lasts steps before clinical translation.