Akio Iwanami相关文献与解析，生知库 | 链接生命科学的每一步

Go Itakura, Soya Kawabata, Miki Ando, Yuichiro Nishiyama, Keiko Sugai, Masahiro Ozaki, Tsuyoshi Iida, Toshiki Ookubo, Kota Kojima, Rei Kashiwagi, Kaori Yasutake, Hiromitsu Nakauchi, Hiroyuki Miyoshi, Narihito Nagoshi, Jun Kohyama, Akio Iwanami, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano

肿瘤

发表日期：2017

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Low immunogenicity of mouse induced pluripotent stem cell-derived neural stem/progenitor cells

小鼠诱导多能干细胞衍生的神经干/祖细胞的低免疫原性

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-017-13522-w

Go Itakura, Masahiro Ozaki, Narihito Nagoshi, Soya Kawabata, Yuichiro Nishiyama, Keiko Sugai, Tsuyoshi Iida, Rei Kashiwagi, Toshiki Ookubo, Kaori Yastake, Kohei Matsubayashi, Jun Kohyama, Akio Iwanami, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano

Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury

使用 γ-分泌酶抑制剂进行预处理可防止脊髓损伤患者的人类 iPSC 衍生移植中出现肿瘤样过度生长

期刊:Stem Cell Reports

影响因子:5.9

doi:10.1016/j.stemcr.2016.08.015

Toshiki Okubo, Akio Iwanami, Jun Kohyama, Go Itakura, Soya Kawabata, Yuichiro Nishiyama, Keiko Sugai, Masahiro Ozaki, Tsuyoshi Iida, Kohei Matsubayashi, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano

Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury

移植人类 iPS 细胞衍生的少突胶质细胞前体细胞有助于脊髓损伤后脱髓鞘轴突的强劲髓鞘再生

期刊:Stem Cell Reports

影响因子:5.9

doi:10.1016/j.stemcr.2015.11.013

Soya Kawabata, Morito Takano, Yuko Numasawa-Kuroiwa, Go Itakura, Yoshiomi Kobayashi, Yuichiro Nishiyama, Keiko Sugai, Soraya Nishimura, Hiroki Iwai, Miho Isoda, Shinsuke Shibata, Jun Kohyama, Akio Iwanami, Yoshiaki Toyama, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano

Robust production of human neural cells by establishing neuroepithelial-like stem cells from peripheral blood mononuclear cell-derived feeder-free iPSCs under xeno-free conditions

在无异种动物条件下，通过从外周血单核细胞衍生的无饲养层 iPSC 建立神经上皮样干细胞来稳定地生产人类神经细胞

期刊:Neuroscience Research

影响因子:2.4

doi:10.1016/j.neures.2016.04.003

Miho Isoda, Jun Kohyama, Akio Iwanami, Tsukasa Sanosaka, Keiko Sugai, Ryo Yamaguchi, Takuya Matsumoto, Masaya Nakamura, Hideyuki Okano

PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies

PML 介导胶质母细胞瘤对哺乳动物雷帕霉素靶标 (mTOR) 靶向疗法的耐药性

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.1217602110

Akio Iwanami, Beatrice Gini, Ciro Zanca, Tomoo Matsutani, Alvaro Assuncao, Ali Nael, Julie Dang, Huijun Yang, Shaojun Zhu, Jun Kohyama, Issay Kitabayashi, Webster K Cavenee, Timothy F Cloughesy, Frank B Furnari, Masaya Nakamura, Yoshiaki Toyama, Hideyuki Okano, Paul S Mischel

A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma

果蝇胶质细胞中的全激酶组 RNAi 筛选表明，RIO 激酶通过胶质母细胞瘤中的 TORC2-Akt 信号传导介导细胞增殖和存活

期刊:PLoS Genetics

影响因子:

doi:10.1371/journal.pgen.1003253

Renee D Read, Tim R Fenton, German G Gomez, Jill Wykosky, Scott R Vandenberg, Ivan Babic, Akio Iwanami, Huijun Yang, Webster K Cavenee, Paul S Mischel, Frank B Furnari, John B Thomas

Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors

胶质瘤和肺癌特异性 EGFR 突变对 EGFR 激酶抑制剂的不同敏感性

期刊:Cancer Discovery

影响因子:29.7

doi:10.1158/2159-8290.CD-11-0284

Igor Vivanco, H Ian Robins, Daniel Rohle, Carl Campos, Christian Grommes, Phioanh Leia Nghiemphu, Sara Kubek, Barbara Oldrini, Milan G Chheda, Nicolas Yannuzzi, Hui Tao, Shaojun Zhu, Akio Iwanami, Daisuke Kuga, Julie Dang, Alicia Pedraza, Cameron W Brennan, Adriana Heguy, Linda M Liau, Frank Lieberm

RNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathways

RNA 结合蛋白 Musashi1 通过转录后调控 Notch 和 PI3 激酶/Akt 信号通路来调节神经胶质瘤细胞生长

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0033431

Jun Muto, Takao Imai, Daisuke Ogawa, Yoshinori Nishimoto, Yohei Okada, Yo Mabuchi, Takeshi Kawase, Akio Iwanami, Paul S Mischel, Hideyuki Saya, Kazunari Yoshida, Yumi Matsuzaki, Hideyuki Okano

An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway

LXR 激动剂通过抑制 EGFR/AKT/SREBP-1/LDLR 依赖性通路促进胶质母细胞瘤细胞死亡

期刊:Cancer Discovery

影响因子:29.7

doi:10.1158/2159-8290.CD-11-0102

Deliang Guo, Felicia Reinitz, Mary Youssef, Cynthia Hong, David Nathanson, David Akhavan, Daisuke Kuga, Ali Nael Amzajerdi, Horacio Soto, Shaojun Zhu, Ivan Babic, Kazuhiro Tanaka, Julie Dang, Akio Iwanami, Beatrice Gini, Jason Dejesus, Dominique D Lisiero, Tiffany T Huang, Robert M Prins, Patrick Y

Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives

针对 iPSC 衍生物移植后潜在致瘤性的故障安全系统

Low immunogenicity of mouse induced pluripotent stem cell-derived neural stem/progenitor cells

小鼠诱导多能干细胞衍生的神经干/祖细胞的低免疫原性

Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury

使用 γ-分泌酶抑制剂进行预处理可防止脊髓损伤患者的人类 iPSC 衍生移植中出现肿瘤样过度生长

Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury

移植人类 iPS 细胞衍生的少突胶质细胞前体细胞有助于脊髓损伤后脱髓鞘轴突的强劲髓鞘再生

Robust production of human neural cells by establishing neuroepithelial-like stem cells from peripheral blood mononuclear cell-derived feeder-free iPSCs under xeno-free conditions

在无异种动物条件下，通过从外周血单核细胞衍生的无饲养层 iPSC 建立神经上皮样干细胞来稳定地生产人类神经细胞

PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies

PML 介导胶质母细胞瘤对哺乳动物雷帕霉素靶标 (mTOR) 靶向疗法的耐药性

A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma

果蝇胶质细胞中的全激酶组 RNAi 筛选表明，RIO 激酶通过胶质母细胞瘤中的 TORC2-Akt 信号传导介导细胞增殖和存活

Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors

胶质瘤和肺癌特异性 EGFR 突变对 EGFR 激酶抑制剂的不同敏感性

RNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathways

RNA 结合蛋白 Musashi1 通过转录后调控 Notch 和 PI3 激酶/Akt 信号通路来调节神经胶质瘤细胞生长

An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway

LXR 激动剂通过抑制 EGFR/AKT/SREBP-1/LDLR 依赖性通路促进胶质母细胞瘤细胞死亡