PD-1 regulates the anti-tumor immune function of macrophages through JAK2-STAT3 signaling pathway in colorectal cancer tumor microenvironment
PD-1通过JAK2-STAT3信号通路调节结直肠癌肿瘤微环境中巨噬细胞的抗肿瘤免疫功能
期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-025-06469-4
Jiang, Han; Pang, Jingjing; Li, Tengyue; Akofala, Atitso; Zhou, Xiaoxi; Yi, Changhua; Ning, Shangwei; Gao, Xu; Qiao, Yu; Kou, Jiayuan
巨噬细胞
肿瘤
肠癌
肿瘤免疫
JAK/STAT
信号转导
巨噬细胞
JAK2
STAT3
细胞生物学
肿瘤微环境
PD-1
免疫/内分泌
