Probing the correlation between ligand efficacy and conformational diversity at the α1A-adrenoreceptor reveals allosteric coupling of its microswitches
探究 α1A 肾上腺素受体的配体功效与构象多样性之间的相关性,揭示其微开关的变构耦合
期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1074/jbc.RA120.012842
Feng-Jie Wu, Lisa M Williams, Alaa Abdul-Ridha, Avanka Gunatilaka, Tasneem M Vaid, Martina Kocan, Alice R Whitehead, Michael D W Griffin, Ross A D Bathgate, Daniel J Scott, Paul R Gooley