日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Coordinated repression of totipotency-associated gene loci by histone methyltransferase EHMT2 via LINE1 regulatory elements

组蛋白甲基转移酶 EHMT2 通过 LINE1 调控元件协同抑制全能性相关基因位点。

Kaushiki Chatterjee #,Christopher Mitsuo Uyehara #,Kritika Kasliwal,Subhashini Madhuranath,Laurianne Scourzic,Alexander Polyzos,Effie Apostolou,Matthias Stadtfeld

Disruption of TAD hierarchy promotes LTR co-option in cancer

TAD层级结构的破坏促进了癌症中LTR的共选。

Elissa W P Wong #,Merve Sahin #,Rui Yang,UkJin Lee,Dan Li,Yingqian A Zhan,Rohan Misra,Fanny Tomas,Nawaf Alomran,Alexander Polyzos,Cindy J Lee,Tuan Trieu,Alexander Martinez-Fundichely,Thomas Wiesner,Andrew Rosowicz,Shuyuan Cheng,Christina Liu,Morgan Lallo,Alexander N Shoushtari,Taha Merghoub,Pierre-Jacques Hamard,Richard Koche,Ekta Khurana,Effie Apostolou,Deyou Zheng,Yu Chen,Christina S Leslie,Ping Chi

3D chromatin hubs as regulatory units of identity and survival in human acute leukemia

3D染色质枢纽作为人类急性白血病中身份和存活的调控单元

Giovanni Gambi ,Francesco Boccalatte ,Javier Rodriguez Hernaez ,Ziyan Lin ,Bettina Nadorp ,Alexander Polyzos ,Jimin Tan ,Kleopatra Avrampou ,Giorgio Inghirami ,Alex Kentsis ,Effie Apostolou ,Iannis Aifantis ,Aristotelis Tsirigos

Enhancer remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm

OTX2介导的增强子重塑指导哺乳动物终末内胚层的分化和模式形成

Ly-Sha Ee ,Daniel Medina-Cano ,Emily Goetzler ,Christopher Uyehara ,Clayton Schwarz ,Eralda Salataj ,Subhashini Madhuranath ,Todd Evans ,Anna-Katerina Hadjantonakis ,Effie Apostolou ,Alexander Polyzos ,Thomas Vierbuchen ,Matthias Stadtfeld

Single-cell analysis of bidirectional reprogramming between early embryonic states identify mechanisms of differential lineage plasticities in mice

通过对早期胚胎状态间双向重编程的单细胞分析,揭示了小鼠谱系可塑性差异的机制。

Vidur Garg,Yang Yang,Sonja Nowotschin,Manu Setty,Eralda Salataj,Ying-Yi Kuo,Dylan Murphy,Roshan Sharma,Amy Jang,Alexander Polyzos,Dana Pe'er,Effie Apostolou,Anna-Katerina Hadjantonakis

3D Enhancer-promoter networks provide predictive features for gene expression and coregulation in early embryonic lineages

3D 增强子-启动子网络为早期胚胎谱系中的基因表达和共调节提供预测特征

Dylan Murphy #, Eralda Salataj #, Dafne Campigli Di Giammartino, Javier Rodriguez-Hernaez, Andreas Kloetgen, Vidur Garg, Erin Char, Christopher M Uyehara, Ly-Sha Ee, UkJin Lee, Matthias Stadtfeld, Anna-Katerina Hadjantonakis, Aristotelis Tsirigos, Alexander Polyzos, Effie Apostolou

An Unbiased Approach to Identifying Cellular Reprogramming-Inducible Enhancers

一种识别细胞重编程诱导增强子的无偏方法

Eleftheria Klagkou,Dimitrios Valakos,Spyros Foutadakis,Alexander Polyzos,Angeliki Papadopoulou,Giannis Vatsellas,Dimitris Thanos

Single-cell analysis of bidirectional reprogramming between early embryonic states reveals mechanisms of differential lineage plasticities

早期胚胎状态间双向重编程的单细胞分析揭示了差异谱系可塑性的机制

Vidur Garg, Yang Yang, Sonja Nowotschin, Manu Setty, Ying-Yi Kuo, Roshan Sharma, Alexander Polyzos, Eralda Salataj, Dylan Murphy, Amy Jang, Dana Pe'er, Effie Apostolou, Anna-Katerina Hadjantonakis

Systematic mapping and modeling of 3D enhancer-promoter interactions in early mouse embryonic lineages reveal regulatory principles that determine the levels and cell-type specificity of gene expression

小鼠早期胚胎谱系中 3D 增强子-启动子相互作用的系统映射和建模揭示了决定基因表达水平和细胞类型特异性的调控原则

Dylan Murphy, Eralda Salataj, Dafne Campigli Di Giammartino, Javier Rodriguez-Hernaez, Andreas Kloetgen, Vidur Garg, Erin Char, Christopher M Uyehara, Ly-Sha Ee, UkJin Lee, Matthias Stadtfeld, Anna-Katerina Hadjantonakis, Aristotelis Tsirigos, Alexander Polyzos, Effie Apostolou

A Knock-In Mouse Model of Thymoma With the GTF2I L424H Mutation

带有 GTF2I L424H 突变的胸腺瘤基因敲入小鼠模型

Yongfeng He, In-Kyu Kim, Jing Bian, Alexander Polyzos, Dafne Campigli Di Giammartino, Yu-Wen Zhang, Ji Luo, Maria O Hernandez, Noemi Kedei, Maggie Cam, Alain C Borczuk, Trevor Lee, Yumin Han, Elizabeth A Conner, Madeline Wong, Desiree C Tillo, Shigeki Umemura, Vincent Chen, Lydia Ruan, Jessica B Whi