日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multi-omic integration identifies broad drug resistance mechanisms and strategies to therapeutically reprogram cancer cells

多组学整合揭示了广泛的耐药机制和治疗性重编程癌细胞的策略

Mersich, Ian; Blagg, Brian S J; Ali, Aktar

Engineered Age-Mimetic Breast Cancer Models Reveal Differential Drug Responses in Young and Aged Microenvironments.

工程化模拟衰老的乳腺癌模型揭示了年轻和衰老微环境中不同的药物反应

Yang Jun, Hawthorne Lauren, Stack Sharon, Blagg Brian, Ali Aktar, Zorlutuna Pinar

Integrative Multi-Omics Analyses Reveal Mechanisms of Resistance to Hsp90β-Selective Inhibition

整合多组学分析揭示Hsp90β选择性抑制的耐药机制

Mersich, Ian; Anik, Eahsanul; Ali, Aktar; Blagg, Brian S J

Synergistic Disruption of Survival and Metastatic Potential in Esophageal Adenocarcinoma Cells Through Combined Inhibition of HIF1α and CD73

通过联合抑制HIF1α和CD73,协同破坏食管腺癌细胞的存活和转移潜能

Mersich, Ian; Malmberg, Alexander; Anik, Eahsanul; Hassan, Md Sazzad; von Holzen, Urs; Blagg, Brian S J; Ali, Aktar

Hsp90β-Selective Inhibitors: Probing the Solvent-Accessible Frontier

Hsp90β选择性抑制剂:探索溶剂可及前沿

D'Amico, Terin; Serwetnyk, Michael A; Dou, Xiaozheng; Mersich, Ian; Barlow, Deborah; Houseknecht, Karen L; Streicher, John M; Ali, Aktar; Blagg, Brian S J

Investigation of GSTP1 and PTEN gene polymorphisms and their association with susceptibility to colorectal cancer.

研究 GSTP1 和 PTEN 基因多态性及其与结直肠癌易感性的关系

Durr-E-Shahwar, Zubair Hina, Raza Muhammad Kashif, Khan Zahid, Mansour Lamjed, Ali Aktar, Imran Muhammad

Instant fluorescence lifetime imaging microscopy reveals mechano-metabolic reprogramming of stromal cells in breast cancer peritumoral microenvironments.

即时荧光寿命成像显微镜揭示了乳腺癌肿瘤周围微环境中基质细胞的机械代谢重编程

Najera Julian, Chen Hao, Batista Bianca, Ketchum Frank, Ali Aktar, Zorlutuna Pinar, Howard Scott, Datta Meenal

Adipocyte Xbp1s overexpression drives uridine production and reduces obesity

脂肪细胞Xbp1s过表达可促进尿苷生成并减少肥胖

Deng, Yingfeng; Wang, Zhao V; Gordillo, Ruth; Zhu, Yi; Ali, Aktar; Zhang, Chen; Wang, Xiaoding; Shao, Mengle; Zhang, Zhuzhen; Iyengar, Puneeth; Gupta, Rana K; Horton, Jay D; Hill, Joseph A; Scherer, Philipp E

Assessment of epicardial adipose tissue thickness and the mean platelet volume in children with familial Mediterranean fever

对患有家族性地中海热的儿童进行心外膜脂肪组织厚度和平均血小板体积的评估

Uluca, Ünal; Demir, Fikri; Ece, Aydın; Şen, Velat; Güneş, Ali; Aktar, Fesih; Tan, İlhan; Karabel, Duran; Yazgan, Ümitcan; Sabaz, Muhammed Nurullah

Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling

小鼠Samd4基因突变会导致消瘦、肌病、线粒体呼吸解偶联和mTORC1信号传导失调。

Chen, Zhe; Holland, William; Shelton, John M; Ali, Aktar; Zhan, Xiaoming; Won, Sungyong; Tomisato, Wataru; Liu, Chen; Li, Xiaohong; Moresco, Eva Marie Y; Beutler, Bruce