日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Assessing Longitudinal Treatment Efficacies and Alterations in Molecular Markers Associated with Glutamatergic Signaling and Immune Checkpoint Inhibitors in a Spontaneous Melanoma Mouse Model

评估自发性黑色素瘤小鼠模型的纵向治疗效果以及与谷氨酸信号和免疫检查点抑制剂相关的分子标记物的变化

Kevinn Eddy, Kajal Gupta, Mohamad Naser Eddin, Christina Marinaro, Sanjana Putta, John Michael Sauer Jr, Anna Chaly, Katie B Freeman, Jeffrey C Pelletier, Anna Fateeva, Philip Furmanski, Ann W Silk, Allen B Reitz, Andrew Zloza, Suzie Chen

Tuning isoform selectivity and bortezomib sensitivity with a new class of alkenyl indene PDI inhibitor

使用新型烯基茚 PDI 抑制剂调节异构体选择性和硼替佐米敏感性

Reeder M Robinson, Leticia Reyes, Ravyn M Duncan, Haiyan Bian, Eric D Strobel, Sarah L Hyman, Allen B Reitz, Nathan G Dolloff

Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA

生物物理筛选鉴定出与病毒 DNA 结合蛋白 EBNA1 和 LANA 结合的片段

Troy E Messick, Lois Tolvinski, Edward R Zartler, Anna Moberg, Åsa Frostell, Garry R Smith, Allen B Reitz, Paul M Lieberman

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth

基于结构设计的小分子 EBNA1 DNA 结合抑制剂可阻断 Epstein-Barr 病毒潜伏感染和肿瘤生长

Troy E Messick, Garry R Smith, Samantha S Soldan, Mark E McDonnell, Julianna S Deakyne, Kimberly A Malecka, Lois Tolvinski, A Pieter J van den Heuvel, Bai-Wei Gu, Joel A Cassel, Donna H Tran, Benjamin R Wassermann, Yan Zhang, Venkata Velvadapu, Edward R Zartler, Pierre Busson, Allen B Reitz, Paul M

Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma

蛋白质二硫键异构酶家族抑制剂用于治疗多发性骨髓瘤

Reeder M Robinson, Leticia Reyes, Ravyn M Duncan, Haiyan Bian, Allen B Reitz, Yefim Manevich, Jesse J McClure, Matthew M Champion, C James Chou, Meahgen E Sharik, Marta Chesi, P Leif Bergsagel, Nathan G Dolloff

Non-NAD-like PARP-1 inhibitors in prostate cancer treatment

非 NAD 样 PARP-1 抑制剂在前列腺癌治疗中的应用

Yaroslava Karpova, Chao Wu, Ali Divan, Mark E McDonnell, Elizabeth Hewlett, Peter Makhov, John Gordon, Min Ye, Allen B Reitz, Wayne E Childers, Tomasz Skorski, Vladimir Kolenko, Alexei V Tulin

Mutation and structure guided discovery of an antiviral small molecule that mimics an essential C-Terminal tripeptide of the vaccinia D4 processivity factor

突变和结构引导发现一种抗病毒小分子,该分子模仿痘苗病毒 D4 加工因子的必需 C 端三肽

Manunya Nuth, Hancheng Guan, Yuhong Xiao, John L Kulp 3rd, Michael H Parker, Eric D Strobel, Stuart N Isaacs, Richard W Scott, Allen B Reitz, Robert P Ricciardi

Synthetic cathinone MDPV enhances reward function through purinergic P2X7 receptor-dependent pathway and increases P2X7 gene expression in nucleus accumbens

合成卡西酮 MDPV 通过嘌呤能 P2X7 受体依赖途径增强奖赏功能,并增加伏隔核中 P2X7 基因的表达

Taylor A Gentile, Steven J Simmons, Christopher S Tallarida, Shu Su, Slava Rom, Mia N Watson, Allen B Reitz, Raghava Potula, Scott M Rawls

Effects of dopaminergic and serotonergic compounds in rats trained to discriminate a high and a low training dose of the synthetic cathinone mephedrone

多巴胺能和血清素能化合物对训练大鼠辨别合成卡西酮高剂量和低剂量的影响

Iman Saber, Andrew Milewski, Allen B Reitz, Scott M Rawls, Ellen A Walker

Glutamate carboxypeptidase II (GCPII) inhibitor 2-PMPA reduces rewarding effects of the synthetic cathinone MDPV in rats: a role for N-acetylaspartylglutamate (NAAG)

谷氨酸羧肽酶 II (GCPII) 抑制剂 2-PMPA 降低合成卡西酮 MDPV 对大鼠的奖励效应:N-乙酰天冬氨酰谷氨酸 (NAAG) 的作用

Callum Hicks, Ryan A Gregg, Sunil U Nayak, Lee Anne Cannella, Giana J Schena, Christopher S Tallarida, Allen B Reitz, Garry R Smith, Scott M Rawls