日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sensitivity to targeted therapy differs between HER2-amplified breast cancer cells harboring kinase and helical domain mutations in PIK3CA

携带 PIK3CA 激酶和螺旋结构域突变的 HER2 扩增乳腺癌细胞对靶向治疗的敏感性不同

Joseph P Garay, Rebecca Smith, Kaylyn Devlin, Daniel P Hollern, Tiera Liby, Moqing Liu, Shanta Boddapati, Spencer S Watson, Amanda Esch, Ting Zheng, Wallace Thompson, Darcie Babcock, Sunjong Kwon, Koei Chin, Laura Heiser, Joe W Gray #, James E Korkola #

Multidimensional profiling of drug-treated cells by Imaging Mass Cytometry

通过成像质谱流式细胞术对药物处理细胞进行多维分析

Alexandre Bouzekri, Amanda Esch, Olga Ornatsky

Combating subclonal evolution of resistant cancer phenotypes

对抗耐药癌症表型的亚克隆进化

Samuel W Brady, Jasmine A McQuerry, Yi Qiao, Stephen R Piccolo, Gajendra Shrestha, David F Jenkins, Ryan M Layer, Brent S Pedersen, Ryan H Miller, Amanda Esch, Sara R Selitsky, Joel S Parker, Layla A Anderson, Brian K Dalley, Rachel E Factor, Chakravarthy B Reddy, Jonathan P Boltax, Dean Y Li, Phili

Pathway-Enriched Gene Signature Associated with 53BP1 Response to PARP Inhibition in Triple-Negative Breast Cancer

三阴性乳腺癌中与 53BP1 对 PARP 抑制反应相关的通路富集基因特征

Saima Hassan, Amanda Esch, Tiera Liby, Joe W Gray, Laura M Heiser

PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder

PEG-脂质胶束促进尼曼匹克 C1 型溶酶体贮积症中的胆固醇流出

Anna Brown, Siddharth Patel, Carl Ward, Anna Lorenz, Mauren Ortiz, Allison DuRoss, Fabian Wieghardt, Amanda Esch, Elsje G Otten, Laura M Heiser, Viktor I Korolchuk, Conroy Sun, Sovan Sarkar, Gaurav Sahay

Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

通过突变分离 PI3K 通路需要对 HER2+ 乳腺癌进行联合治疗

James E Korkola, Eric A Collisson, Laura Heiser, Chris Oates, Nora Bayani, Sleiman Itani, Amanda Esch, Wallace Thompson, Obi L Griffith, Nicholas J Wang, Wen-Lin Kuo, Brian Cooper, Jessica Billig, Safiyyah Ziyad, Jenny L Hung, Lakshmi Jakkula, Heidi Feiler, Yiling Lu, Gordon B Mills, Paul T Spellman