日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genomic Profiling Identifies Outcome-Relevant Mechanisms of Innate and Acquired Resistance to Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy in Lung Cancer

基因组分析揭示肺癌中与第三代表皮生长因子受体酪氨酸激酶抑制剂治疗相关的先天性和获得性耐药机制

Michels, Sebastian; Heydt, Carina; van Veggel, Bianca; Deschler-Baier, Barbara; Pardo, Nuria; Monkhorst, Kim; Rüsseler, Vanessa; Stratmann, Jan; Griesinger, Frank; Steinhauser, Susanne; Kostenko, Anna; Diebold, Joachim; Fassunke, Jana; Fischer, Rieke; Engel-Riedel, Walburga; Gautschi, Oliver; Geissinger, Eva; Haneder, Stefan; Ihle, Michaela A; Kopp, Hans-Georg; de Langen, Adrianus J; Martinez-Marti, Alex; Nogova, Lucia; Persigehl, Thorsten; Plenker, Dennis; Puesken, Michael; Rodermann, Ernst; Rosenwald, Andreas; Scheel, Andreas H; Scheffler, Matthias; Spengler, Werner; Seggewiss-Bernhardt, Ruth; Brägelmann, Johannes; Sebastian, Martin; Vrugt, Bart; Hellmich, Martin; Sos, Martin L; Heukamp, Lukas C; Felip, Enriqueta; Merkelbach-Bruse, Sabine; Smit, Egbert F; Büttner, Reinhard; Wolf, Jürgen

Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation

Bcl-xL 介导间充质乳腺癌细胞亚群的治疗耐药性

Ulrike Keitel, Andreas Scheel, Jürgen Thomale, Rovena Halpape, Silke Kaulfuß, Christina Scheel, Matthias Dobbelstein

While p73 is essential, p63 is completely dispensable for the development of the central nervous system

虽然 p73 是必需的,但 p63 对于中枢神经系统的发育来说却是完全可有可无的

Lena Holembowski, Ramona Schulz, Flaminia Talos, Andreas Scheel, Sonja Wolff, Matthias Dobbelstein, Ute Moll

A profiling platform for the characterization of transglutaminase 2 (TG2) inhibitors

用于表征转谷氨酰胺酶 2 (TG2) 抑制剂的分析平台

Sabine Schaertl, Michael Prime, John Wityak, Celia Dominguez, Ignacio Munoz-Sanjuan, Robert E Pacifici, Stephen Courtney, Andreas Scheel, Douglas Macdonald