日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

First-in-class anti-human CD45RC antibody targets CD45RC(high) T and B cells to mitigate pathogenic immune responses

首创的抗人CD45RC抗体靶向CD45RC(high) T细胞和B细胞,以减轻致病性免疫反应。

Bergua, Cécile; Ahmil-Boiteau, Ghenima; Ouisse, Laure-Hélène; Vimond, Nadège; Sérazin, Céline; Dugast, Lisa; Humeau, Romain; Salama, Apolline; Tesson, Laurent; Swinnen, Katleen; Van Brempt, Ronald; Collette, Alexis; Anegon, Ignacio; Guillonneau, Carole

Inactivation of the Phosphatase Activity of Soluble Epoxide Hydrolase Modulates SIRT3 and Attenuates Experimental Pulmonary Hypertension

可溶性环氧化物水解酶磷酸酶活性的失活调节SIRT3并减轻实验性肺动脉高压

Leuillier, Matthieu; Chelgham, Mustapha; Messaoudi, Hind; Tu, Ly; Ménoret, Severine; Thuillet, Raphaël; Groussard, Déborah; Lillich, Felix F; Ottaviani, Mina; Nicol, Lionel; Mulder, Paul; Humbert, Marc; Richard, Vincent; Anegon, Ignacio; Morisseau, Christophe; Proschak, Ewgenij; Guignabert, Christophe; Bellien, Jérémy

New soluble CSF-1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in pleural mesothelioma

新型可溶性 CSF-1R 二聚体突变体可增强对 CSF-1 和 IL-34 的捕获能力,从而减少胸膜间皮瘤中具有抑制作用的肿瘤相关巨噬细胞。

Noémie Joalland ,Agnès Quéméner ,Sophie Deshayes ,Romain Humeau ,Mike Maillasson ,Héloïse LeBihan ,Apolline Salama ,Judith Fresquet ,Séverine Remy ,Erwan Mortier # ,Christophe Blanquart # ,Carole Guillonneau # ,Ignacio Anegon #

The phosphatase activity of soluble epoxide hydrolase regulates vascular calcification through the metabolism of pyrophosphate anions

可溶性环氧化物水解酶的磷酸酶活性通过焦磷酸根阴离子的代谢来调节血管钙化。

Messaoudi, Hind; Varennes, Olivier; Berg, Elodie; Perzo, Nicolas; Renet, Sylvanie; Chegrani, Ghiles; Duflot, Thomas; Feugray, Guillaume; Lillich, Felix F; Kauffenstein, Gilles; Brunel, Valéry; Six, Isabelle; Mentaverri, Romuald; Richard, Vincent; Anegon, Ignacio; Morisseau, Christophe; Kamel, Saïd; Proschak, Ewgenij; Bellien, Jérémy

Vascular endothelial cells derived from transgene-free pig induced pluripotent stem cells for vascular tissue engineering

源自无转基因猪诱导多能干细胞的血管内皮细胞用于血管组织工程

Luke Batty ,Jinkyu Park ,Lingfeng Qin ,Muhammad Riaz ,Yuyao Lin ,Zhen Xu ,Xuefei Gao ,Xin Li ,Colleen Lopez ,Wei Zhang ,Marie Hoareau ,Meghan E Fallon ,Yan Huang ,Hangqi Luo ,Jiesi Luo ,Séverine Ménoret ,Peining Li ,Zhenting Jiang ,Peter Smith ,David H Sachs ,George Tellides ,Ignacio Anegon ,Jordan S Pober ,Pentao Liu ,Yibing Qyang

Bone morphogenetic protein-9 controls pulmonary vascular growth and remodeling

骨形态发生蛋白-9控制肺血管生长和重塑

Berrebeh, Nihel; Mbouamboua, Yvon; Thuillet, Raphaël; Ottaviani, Mina; Robert, Fabien; Kamel Chelgham, Mustapha; Magnone, Virginie; Desroches-Castan, Agnès; Ricard, Nicolas; Anegon, Ignacio; Remy, Séverine; Schermuly, Ralph Theo; Lebrigand, Kevin; Kojonazarov, Baktybek; Savale, Laurent; Humbert, Marc; Bailly, Sabine; Barbry, Pascal; Tu, Ly; Guignabert, Christophe

Phenotypic characterization of an Atp13a2 knockout rat model of Parkinson's disease.

帕金森病 Atp13a2 基因敲除大鼠模型的表型特征分析。

Kinet Rémi, Sikora Joanna, Arotcarena Marie-Laure, Decourt Melina, Balado Eric, Doudnikoff Evelyne, Bohic Sylvain, Vesnaver Marta, Lovisotto Anna, Thiolat Marie-Laure, Dutheil Nathalie, Mazzocco Claire, Harhouri Karim, Steinschneider Rémy, Menoret Severine, Tesson Laurent, Anegon Ignacio, Morari Michele, Vila Miquel, Georges François, Bezard Erwan, Fernagut Pierre-Olivier, Dehay Benjamin

Combination of Orai1 inhibitor CM5480 with specific therapy mitigates pulmonary hypertension and its cardiac dysfunction

Orai1抑制剂CM5480联合特定疗法可减轻肺动脉高压及其心脏功能障碍

Willer, Anaïs Saint-Martin; Ruffenach, Grégoire; Masson, Bastien; El Jekmek, Kristelle; Boët, Angèle; Adão, Rui; Gourmelon, Mathieu; Beauvais, Antoine; Sabourin, Jessica; Dutheil, Mary; Ghigna, Maria-Rosa; Tesson, Laurent; Ménoret, Séverine; Anegon, Ignacio; Bauer, Fabrice; de Montpréville, Vincent; Hebbar, Sudarshan; Brás-Silva, Carmen; Stauderman, Kenneth; Humbert, Marc; Mercier, Olaf; Montani, David; Capuano, Véronique; Antigny, Fabrice

Human pluripotent stem cell-derived hepatic progenitors exhibit a partially hypoimmunogenic phenotype and actively inhibit immune responses

人多能干细胞来源的肝脏祖细胞表现出部分低免疫原性表型,并能主动抑制免疫反应。

Gantier, Malika; Ménoret, Séverine; Fourrier, Angélique; Delbos, Frédéric; Nguyen, Tuan Huy; Anegon, Ignacio

Two subsets of regulatory CD8+ T cells with differential transcriptome revealed by single cell analysis

单细胞分析揭示了两种具有差异转录组的调节性CD8+ T细胞亚群

Céline Sérazin ,Lisa Dugast ,Léa Flippe ,Mathias Streitz ,Désirée-Jacqueline Wendering ,Stephan Schlickeiser ,Frederik Heinrich ,Pawel Durek ,Gabriela Maria Guerra ,Katrin Lehmann ,Mir-Farzin Mashreghi ,Harald Wajant ,Hans Dieter Volk ,Ignacio Anegon ,Laurent David ,Séverine Bézie ,Carole Guillonneau