A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 receptor
基于结构的药物设计鉴定出的一种多环骨架能有效抑制人P2X7受体。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-62643-8
Oken, Adam C; Turcu, Andreea L; Tzortzini, Eva; Georgiou, Kyriakos; Nagel, Jessica; Westermann, Franka G; Barniol-Xicota, Marta; Seidler, Jonas; Kim, Ga-Ram; Lee, So-Deok; Nicke, Annette; Kim, Yong-Chul; Müller, Christa E; Kolocouris, Antonios; Vázquez, Santiago; Mansoor, Steven E
