日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Neuroprotective Effects of σ(2)R/TMEM97 Receptor Modulators in the Neuronal Model of Huntington's Disease

σ(2)R/TMEM97受体调节剂在亨廷顿病神经元模型中的神经保护作用

期刊:ACS Chemical Neuroscience
影响因子:3.9
doi:10.1021/acschemneuro.2c00274
Jin, Jing; Arbez, Nicolas; Sahn, James J; Lu, Yan; Linkens, Kathryn T; Hodges, Timothy R; Tang, Anthony; Wiseman, Robyn; Martin, Stephen F; Ross, Christopher A
信号转导
神经科学
发表日期：2022
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Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease

Nemo样激酶可降低突变亨廷顿蛋白水平并减轻亨廷顿病症状。

期刊:Human Molecular Genetics
影响因子:3.2
doi:10.1093/hmg/ddaa061
Jiang, Mali; Zhang, Xiaoyan; Liu, Hongshuai; LeBron, Jared; Alexandris, Athanasios; Peng, Qi; Gu, Hao; Yang, Fanghan; Li, Yuchen; Wang, Ruiling; Hou, Zhipeng; Arbez, Nicolas; Ren, Qianwei; Dong, Jen-Li; Whela, Emma; Wang, Ronald; Ratovitski, Tamara; Troncoso, Juan C; Mori, Susumu; Ross, Christopher A; Lim, Janghoo; Duan, Wenzhen
信号转导
发表日期：2020
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G2019S-LRRK2 mutation enhances MPTP-linked Parkinsonism in mice.

G2019S-LRRK2 突变会增强小鼠中 MPTP 相关的帕金森病症状

期刊:Human Molecular Genetics
影响因子:3.2
doi:10.1093/hmg/ddz271
Arbez Nicolas, He XiaoFei, Huang Yong, Ren Mark, Liang Yideng, Nucifora Frederick C, Wang Xiaofang, Pei Zhong, Tessarolo Lino, Smith Wanli W, Ross Christopher A
神经科学
发表日期：2020
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Cysteamine Protects Neurons from Mutant Huntingtin Toxicity.

半胱胺保护神经元免受突变亨廷顿蛋白毒性的侵害

期刊:Journal of Huntingtons Disease
影响因子:3.1
doi:10.3233/JHD-180312
Arbez Nicolas, Roby Elaine, Akimov Sergey, Eddings Chelsy, Ren Mark, Wang Xiaofang, Ross Christopher A
神经科学
发表日期：2019
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Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1

WSB1通过K27和K29链介导的泛素化作用，可促进LRRK2的聚集并发挥神经元保护作用。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/ncomms11792
Nucifora, Frederick C Jr; Nucifora, Leslie G; Ng, Chee-Hoe; Arbez, Nicolas; Guo, Yajuan; Roby, Elaine; Shani, Vered; Engelender, Simone; Wei, Dong; Wang, Xiao-Fang; Li, Tianxia; Moore, Darren J; Pletnikova, Olga; Troncoso, Juan C; Sawa, Akira; Dawson, Ted M; Smith, Wanli; Lim, Kah-Leong; Ross, Christopher A
LRRK2
泛素化
表观遗传
神经科学
发表日期：2016
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ATXN2-AS, a gene antisense to ATXN2, is associated with spinocerebellar ataxia type 2 and amyotrophic lateral sclerosis

ATXN2-AS是ATXN2的反义基因，与2型脊髓小脑性共济失调和肌萎缩侧索硬化症相关。

期刊:Annals of Neurology
影响因子:7.7
doi:10.1002/ana.24761
Li, Pan P; Sun, Xin; Xia, Guangbin; Arbez, Nicolas; Paul, Sharan; Zhu, Shanshan; Peng, H Benjamin; Ross, Christopher A; Koeppen, Arnulf H; Margolis, Russell L; Pulst, Stefan M; Ashizawa, Tetsuo; Rudnicki, Dobrila D
神经科学
发表日期：2016
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PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD)

PRMT5 介导的对称精氨酸二甲基化作用会被突变的亨廷顿蛋白减弱，并在亨廷顿病 (HD) 中受损。

期刊:Cell Cycle
影响因子:3.4
doi:10.1080/15384101.2015.1033595
Ratovitski, Tamara; Arbez, Nicolas; Stewart, Jacqueline C; Chighladze, Ekaterine; Ross, Christopher A
表观遗传
发表日期：2015
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Presenilin mediates neuroprotective functions of ephrinB and brain-derived neurotrophic factor and regulates ligand-induced internalization and metabolism of EphB2 and TrkB receptors

早老素介导 EphrinB 和脑源性神经营养因子的神经保护功能，并调节 EphB2 和 TrkB 受体的配体诱导内化和代谢。

期刊:Neurobiology of Aging
影响因子:3.5
doi:10.1016/j.neurobiolaging.2012.02.024
Barthet, Gael; Dunys, Julie; Shao, Zhiping; Xuan, Zhao; Ren, Yimin; Xu, Jindong; Arbez, Nicolas; Mauger, Gweltas; Bruban, Julien; Georgakopoulos, Anastasios; Shioi, Junichi; Robakis, Nikolaos K
代谢
信号转导
Trk
神经科学
发表日期：2013
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Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

Sirt1通过激活多个Sirt1靶点在亨廷顿病哺乳动物模型中发挥神经保护作用

期刊:Nature Medicine
影响因子:50
doi:10.1038/nm.2558
Jiang, Mali; Wang, Jiawei; Fu, Jinrong; Du, Lin; Jeong, Hyunkyung; West, Tim; Xiang, Lan; Peng, Qi; Hou, Zhipeng; Cai, Huan; Seredenina, Tamara; Arbez, Nicolas; Zhu, Shanshan; Sommers, Katherine; Qian, Jennifer; Zhang, Jiangyang; Mori, Susumu; Yang, X William; Tamashiro, Kellie L K; Aja, Susan; Moran, Timothy H; Luthi-Carter, Ruth; Martin, Bronwen; Maudsley, Stuart; Mattson, Mark P; Cichewicz, Robert H; Ross, Christopher A; Holtzman, David M; Krainc, Dimitri; Duan, Wenzhen
发表日期：2011
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