日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.

利用高通量肿瘤细胞系分析鉴定与基因型相关的对选择性激酶抑制剂的敏感性

McDermott Ultan, Sharma Sreenath V, Dowell Lori, Greninger Patricia, Montagut Clara, Lamb Jennifer, Archibald Heidi, Raudales Raul, Tam Angela, Lee Diana, Rothenberg S Michael, Supko Jeffrey G, Sordella Raffaella, Ulkus Lindsey E, Iafrate A John, Maheswaran Shyamala, Njauw Ching Ni, Tsao Hensin, Drew Lisa, Hanke Jeff H, Ma Xiao-Jun, Erlander Mark G, Gray Nathanael S, Haber Daniel A, Settleman Jeffrey

Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752.

MET 扩增可能识别出对选择性酪氨酸激酶抑制剂 PHA-665752 极其敏感的癌症亚群

Smolen Gromoslaw A, Sordella Raffaella, Muir Beth, Mohapatra Gayatry, Barmettler Anne, Archibald Heidi, Kim Woo J, Okimoto Ross A, Bell Daphne W, Sgroi Dennis C, Christensen James G, Settleman Jeffrey, Haber Daniel A