日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Adjusting the Preincubation Conditions to Enhance the Ames Test for Detecting the Mutagenicity of N-Nitrosamines

调整预孵育条件以增强Ames试验检测N-亚硝胺致突变性的能力

Bishop, Michelle E; Sims, Audrey M; Guerrero, Sharon K; Mitchell, Kamela; Mei, Nan; Xu, Hannah; Kruhlak, Naomi L; King, Sruthi T; Dorsam, Robert T; Atrakchi, Aisar H; McGovern, Timothy J; Heflich, Robert H

High-Throughput Single-Cell Proteomics of In Vivo Cells

体内细胞的高通量单细胞蛋白质组学

Shiri Karagach ,Joachim Smollich ,Ofir Atrakchi ,Vishnu Mohan ,Tamar Geiger

Comparative DNA damage induced by eight nitrosamines in primary human and macaque hepatocytes

八种亚硝胺对原代人肝细胞和猕猴肝细胞DNA损伤的比较研究

Seo, Ji-Eun; He, Xiaobo; Bryant, Matthew; Atrakchi, Aisar H; McGovern, Timothy J; Davis Bruno, Karen L; Heflich, Robert H; Guo, Xiaoqing

Integration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of 4 small-molecule nitrosamines with different carcinogenic potencies and tumor target specificities

将大鼠肝微核试验整合到 28 天治疗方案中:测试 4 种具有不同致癌效力和肿瘤靶向特异性的小分子亚硝胺的遗传毒性

Guo, Xiaoqing; Seo, Ji-Eun; Xu, Hannah; Yan, Jian; Malhi, Pritpal; Atrakchi, Aisar H; McGovern, Timothy; Davis Bruno, Karen L; Heflich, Robert H; Chen, Tao

Genotoxicity evaluation of ten nitrosamine drug substance-related impurities using 2D and 3D HepaRG cell models

利用二维和三维HepaRG细胞模型对十种亚硝胺类药物相关杂质进行遗传毒性评价

Seo, Ji-Eun; Xu, Hannah; Li, Xilin; Atrakchi, Aisar H; McGovern, Timothy; Davis Bruno, Karen L; Keire, David A; Mei, Nan; Heflich, Robert H; Guo, Xiaoqing

Mutagenicity and genotoxicity evaluation of 15 nitrosamine drug substance-related impurities in human TK6 cells

对15种亚硝胺类药物相关杂质在人TK6细胞中的致突变性和遗传毒性进行评价

Li, Xilin; Le, Yuan; Guo, Xiaoqing; King, Sruthi T; Dorsam, Robert T; Atrakchi, Aisar H; McGovern, Timothy J; Davis-Bruno, Karen L; Keire, David A; Heflich, Robert H; Mei, Nan

Optimizing the detection of N-nitrosamine mutagenicity in the Ames test.

优化 Ames 试验中 N-亚硝胺致突变性的检测

Heflich Robert H, Bishop Michelle E, Mittelstaedt Roberta A, Yan Jian, Guerrero Sharon K, Sims Audrey M, Mitchell Kamela, Moore Nyosha, Li Xilin, Mei Nan, Elespuru Rosalie K, King Sruthi T, Keire David A, Kruhlak Naomi L, Dorsam Robert T, Raw Andre S, Davis Bruno Karen L, McGovern Timothy J, Atrakchi Aisar H

Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell models

利用二维和三维HepaRG细胞模型评估八种亚硝胺的遗传毒性

Seo, Ji-Eun; Yu, Joshua Z; Xu, Hannah; Li, Xilin; Atrakchi, Aisar H; McGovern, Timothy J; Bruno, Karen L Davis; Mei, Nan; Heflich, Robert H; Guo, Xiaoqing

Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays

重新审视 N-亚硝基普萘洛尔在细菌和人体体外试验中的致突变性和遗传毒性

Xilin Li, Yuan Le, Ji-Eun Seo, Xiaoqing Guo, Yuxi Li, Si Chen, Roberta A Mittelstaedt, Nyosha Moore, Sharon Guerrero, Audrey Sims, Sruthi T King, Aisar H Atrakchi, Timothy J McGovern, Karen L Davis-Bruno, David A Keire, Rosalie K Elespuru, Robert H Heflich, Nan Mei

Definition of the contribution of an Osteopontin-producing CD11c+ microglial subset to Alzheimer's disease

骨桥蛋白产生 CD11c+ 小胶质细胞亚群对阿尔茨海默病的贡献的定义

Yiguo Qiu, Xianli Shen, Orly Ravid, Dana Atrakchi, Daniel Rand, Andrew E Wight, Hye-Jung Kim, Sigal Liraz-Zaltsman, Itzik Cooper, Michal Schnaider Beeri, Harvey Cantor