Axel Methner相关文献与解析，生知库 | 链接生命科学的每一步

Marko Jörg #, Johanna E Plehn #, Marco Kristen, Marc Lander, Lukas Walz, Christine Lietz, Julie Wijns, Florian Pichot, Liliana Rojas-Charry, Katja M Wirtz Martin, Nicolas Ruffini, Nastasja Kreim, Susanne Gerber, Yuri Motorin, Kristina Endres, Walter Rossmanith, Axel Methner, Mark Helm, Kristina Frie

神经

阿尔茨海默症

ELISA

发表日期：2024

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GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton

GDAP1功能丧失会通过改变肌动蛋白细胞骨架来抑制线粒体丙酮酸脱氢酶复合物。

期刊:Communications Biology

影响因子:5.2

doi:10.1038/s42003-022-03487-6

Christina Wolf ，Alireza Pouya ，Sara Bitar ，Annika Pfeiffer ，Diones Bueno ，Liliana Rojas-Charry ，Sabine Arndt ，David Gomez-Zepeda ，Stefan Tenzer ，Federica Dal Bello ，Caterina Vianello ，Sandra Ritz ，Jonas Schwirz ，Kristina Dobrindt ，Michael Peitz ，Eva-Maria Hanschmann ，Pauline Mencke ，Ibrahim Boussaad ，Marion Silies ，Oliver Brüstle ，Marta Giacomello ，Rejko Krüger ，Axel Methner

Chronic social stress disrupts the intracellular redistribution of brain hexokinase 3 induced by shifts in peripheral glucose levels

慢性社会压力会破坏由外周血糖水平变化引起的脑己糖激酶 3 的细胞内重新分布

期刊:Journal of Molecular Medicine-Jmm

影响因子:

doi:10.1007/s00109-022-02235-x

Michael A van der Kooij #, Liliana Rojas-Charry #, Maryam Givehchi, Christina Wolf, Diones Bueno, Sabine Arndt, Stefan Tenzer, Lorenzo Mattioni, Giulia Treccani, Annika Hasch, Michael J Schmeisser, Caterina Vianello, Marta Giacomello, Axel Methner

An improved method for precise genome editing in zebrafish using CRISPR-Cas9 technique

一种利用CRISPR-Cas9技术对斑马鱼进行精准基因组编辑的改进方法

期刊:Molecular Biology Reports

影响因子:2.6

doi:10.1007/s11033-020-06125-8

Eugene V Gasanov, Justyna Jędrychowska, Michal Pastor, Malgorzata Wiweger, Axel Methner, Vladimir P Korzh

发表日期：2021

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Transmembrane BAX Inhibitor-1 Motif Containing Protein 5 (TMBIM5) Sustains Mitochondrial Structure, Shape, and Function by Impacting the Mitochondrial Protein Synthesis Machinery

跨膜 BAX 抑制剂-1 基序含蛋白 5 (TMBIM5) 通过影响线粒体蛋白质合成机制来维持线粒体的结构、形状和功能

期刊:Cells

影响因子:5.1

doi:10.3390/cells9102147

Bruno Seitaj, Felicia Maull, Li Zhang, Verena Wüllner, Christina Wolf, Philipp Schippers, Rita La Rovere, Ute Distler, Stefan Tenzer, Jan B Parys, Geert Bultynck, Axel Methner

信号转导

发表日期：2020

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Bax inhibitor-1 deficiency leads to obesity by increasing Ca2+-dependent insulin secretion

Bax 抑制剂 1 缺乏导致肥胖，原因是增加 Ca2+ 依赖性胰岛素分泌

期刊:Journal of Molecular Medicine-Jmm

影响因子:

doi:10.1007/s00109-020-01914-x

Koenraad Philippaert, Michael Roden, Dmitrij Lisak, Diones Bueno, Tomas Jelenik, Konstantin Radyushkin, Teresa Schacht, Margot Mesuere, Verena Wüllner, Ann-Kathrin Herrmann, Jan Baumgart, Rudi Vennekens, Axel Methner

信号转导

发表日期：2020

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The Charcot-Marie Tooth Disease Mutation R94Q in MFN2 Decreases ATP Production but Increases Mitochondrial Respiration under Conditions of Mild Oxidative Stress

MFN2 中的 Charcot-Marie Tooth 病突变 R94Q 会降低 ATP 生成，但在轻度氧化应激条件下会增加线粒体呼吸

期刊:Cells

影响因子:5.1

doi:10.3390/cells8101289

Christina Wolf, Rahel Zimmermann, Osamah Thaher, Diones Bueno, Verena Wüllner, Michael K E Schäfer, Philipp Albrecht, Axel Methner

表观遗传

发表日期：2019

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Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis

缺乏系统 xc- 免疫细胞侵入中枢神经系统可缓解实验性自身免疫性脑炎

期刊:Journal of Neuroinflammation

影响因子:9.3

doi:10.1186/s12974-016-0787-0

Ellen Merckx, Giulia Albertini, Magdalena Paterka, Cathy Jensen, Philipp Albrecht, Michael Dietrich, Joeri Van Liefferinge, Eduard Bentea, Lise Verbruggen, Thomas Demuyser, Lauren Deneyer, Jan Lewerenz, Geert van Loo, Jacques De Keyser, Hideyo Sato, Pamela Maher, Axel Methner, Ann Massie

Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity

Bcl-xL 敲除会减弱线粒体呼吸并引起氧化应激，而戊糖磷酸途径活性可以补偿这种应激

期刊:Free Radical Biology and Medicine

影响因子:7.1

doi:10.1016/j.freeradbiomed.2017.08.007

Annika Pfeiffer, Julia Schneider, Diones Bueno, Amalia Dolga, Timo-Daniel Voss, Jan Lewerenz, Verena Wüllner, Axel Methner

表观遗传

发表日期：2017

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Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase

富马酸二甲酯通过上调谷胱甘肽还原酶诱导谷胱甘肽循环

期刊:Oxidative Medicine and Cellular Longevity

影响因子:

doi:10.1155/2017/6093903

Christina Hoffmann, Michael Dietrich, Ann-Kathrin Herrmann, Teresa Schacht, Philipp Albrecht, Axel Methner

ACTC

发表日期：2017

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N1-methylation of adenosine (m1A) in ND5 mRNA leads to complex I dysfunction in Alzheimer's disease

ND5 mRNA 中腺苷 (m1A) 的 N1-甲基化导致阿尔茨海默病中的复合物 I 功能障碍

GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton

GDAP1功能丧失会通过改变肌动蛋白细胞骨架来抑制线粒体丙酮酸脱氢酶复合物。

Chronic social stress disrupts the intracellular redistribution of brain hexokinase 3 induced by shifts in peripheral glucose levels

慢性社会压力会破坏由外周血糖水平变化引起的脑己糖激酶 3 的细胞内重新分布

An improved method for precise genome editing in zebrafish using CRISPR-Cas9 technique

一种利用CRISPR-Cas9技术对斑马鱼进行精准基因组编辑的改进方法

Transmembrane BAX Inhibitor-1 Motif Containing Protein 5 (TMBIM5) Sustains Mitochondrial Structure, Shape, and Function by Impacting the Mitochondrial Protein Synthesis Machinery

跨膜 BAX 抑制剂-1 基序含蛋白 5 (TMBIM5) 通过影响线粒体蛋白质合成机制来维持线粒体的结构、形状和功能

Bax inhibitor-1 deficiency leads to obesity by increasing Ca2+-dependent insulin secretion

Bax 抑制剂 1 缺乏导致肥胖，原因是增加 Ca2+ 依赖性胰岛素分泌

The Charcot-Marie Tooth Disease Mutation R94Q in MFN2 Decreases ATP Production but Increases Mitochondrial Respiration under Conditions of Mild Oxidative Stress

MFN2 中的 Charcot-Marie Tooth 病突变 R94Q 会降低 ATP 生成，但在轻度氧化应激条件下会增加线粒体呼吸

Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis

缺乏系统 xc- 免疫细胞侵入中枢神经系统可缓解实验性自身免疫性脑炎

Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity

Bcl-xL 敲除会减弱线粒体呼吸并引起氧化应激，而戊糖磷酸途径活性可以补偿这种应激

Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase

富马酸二甲酯通过上调谷胱甘肽还原酶诱导谷胱甘肽循环