日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AI-driven discovery of synergistic drug combinations against pancreatic cancer.

利用人工智能发现对抗胰腺癌的协同药物组合

Pourmousa Mohsen, Jain Sankalp, Barnaeva Elena, Jin Wengong, Hochuli Joshua, Itkin Zina, Maxfield Travis, Melo-Filho Cleber, Thieme Andrew, Wilson Kelli, Klumpp-Thomas Carleen, Michael Sam, Southall Noel, Jaakkola Tommi, Muratov Eugene N, Barzilay Regina, Tropsha Alexander, Ferrer Marc, Zakharov Alexey V

Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro

发现一种促甲状腺激素受体的正向变构调节剂:体外增强促甲状腺激素介导的前成骨细胞分化

Neumann, Susanne; Eliseeva, Elena; Boutin, Alisa; Barnaeva, Elena; Ferrer, Marc; Southall, Noel; Kim, David; Hu, Xin; Morgan, Sarah J; Marugan, Juan J; Gershengorn, Marvin C

Identification of 4-phenylquinolin-2(1H)-one as a specific allosteric inhibitor of Akt

鉴定出 4-苯基喹啉-2(1H)-酮是 Akt 的特异性变构抑制剂

Huang, Bill X; Newcomer, Kenny; Kevala, Karl; Barnaeva, Elena; Zheng, Wei; Hu, Xin; Patnaik, Samarjit; Southall, Noel; Marugan, Juan; Ferrer, Marc; Kim, Hee-Yong

Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus

低剂量依米丁抗人巨细胞病毒的疗效和作用机制

Mukhopadhyay, Rupkatha; Roy, Sujayita; Venkatadri, Rajkumar; Su, Yu-Pin; Ye, Wenjuan; Barnaeva, Elena; Mathews Griner, Lesley; Southall, Noel; Hu, Xin; Wang, Amy Q; Xu, Xin; Dulcey, Andrés E; Marugan, Juan J; Ferrer, Marc; Arav-Boger, Ravit

Structural Insights into the Activation of Human Relaxin Family Peptide Receptor 1 by Small-Molecule Agonists

小分子激动剂激活人松弛素家族肽受体1的结构解析

Hu, Xin; Myhr, Courtney; Huang, Zaohua; Xiao, Jingbo; Barnaeva, Elena; Ho, Brian A; Agoulnik, Irina U; Ferrer, Marc; Marugan, Juan J; Southall, Noel; Agoulnik, Alexander I