Baylink相关文献与解析，生知库 | 链接生命科学的每一步

Franco, Kailie; DiIorio, Megan; Simpkin, Adam J; Keegan, Ronan M; Kallio, Karen; Goers-Sweeney, Emily; Colbert, Michelle; Remington, S James; Cassidy, C Keith; Kulczyk, Arkadiusz W; Baylink, Arden

信号转导

发表日期：2026

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Exploring treatment-driven subclonal evolution of prognostic triple biomarkers: Dual gene fusions and chimeric RNA variants in novel subtypes of acute myeloid leukemia patients with KMT2A rearrangement

探索治疗驱动的预后三重生物标志物的亚克隆演变：KMT2A重排急性髓系白血病患者新亚型中的双基因融合和嵌合RNA变体

期刊:Drug Resistance Updates

影响因子:15.8

doi:10.1016/j.drup.2024.101199

Yi Xu ，Shengwen Calvin Li ，Jeffrey Xiao ，Qian Liu ，Durga Cherukuri ，Yan Liu ，Saied Mirshahidi ，Jane Xu ，Xuelian Chen ，Dadrastoussi Homa ，Julian Olea ，Kaijin Wu ，Kevin R Kelly ，Fengzhu Sun ，Ruihao Huang ，Xiaoqi Wang ，Qin Wen ，Xi Zhang ，Cristina M Ghiuzeli ，Esther Chong ，Hisham Abdel-Azim ，Mark E Reeves ，David J Baylink ，Huynh Cao ，Jiang F Zhong

Targeting DNA helicase CMG complex and NFκB2-driven drug-resistant transcriptional axis to effectively treat KRAS(G12D)-mutated pancreatic cancer

靶向DNA解旋酶CMG复合物和NFκB2驱动的耐药转录轴，以有效治疗KRAS(G12D)突变型胰腺癌

期刊:Experimental Hematology & Oncology

影响因子:13.5

doi:10.1186/s40164-025-00669-w

Xiao, Jeffrey; Kim, Joshua; Park, Brandon; Baylink, David J; Kwon, Cedric; Tran, Victoria; Lee, Scott; Codorniz, Kevin; Tan, Laren; Moreno, Pamela Lobo; Schill-Depew, Amy; Mirshahidi, Saied; De Semir, David; Hanna, Diana; Naqvi, Kiran; Cao, Huynh; Chen, Chien-Shing; Xiu, Joanne; Lenz, Heinz-Josef; Mirshahidi, Hamid; Reeves, Mark E; Xu, Yi

Author Correction: Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage

作者更正：利用 CRISPR/Cas9 介导的双链 DNA 切割，通过双切割 HDR 供体实现高效精确的基因敲入

期刊:Genome Biology

影响因子:9.4

doi:10.1186/s13059-025-03629-z

Zhang, Jian-Ping; Li, Xiao-Lan; Li, Guo-Hua; Chen, Wanqiu; Arakaki, Cameron; Botimer, Gary D; Baylink, David; Zhang, Lu; Wen, Wei; Fu, Ya-Wen; Xu, Jing; Chun, Noah; Yuan, Weiping; Cheng, Tao; Zhang, Xiao-Bing

发表日期：2025

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Nutrient-gene therapy as a strategy to enhance CAR T cell function and overcome barriers in the tumor microenvironment

营养基因疗法作为一种增强CAR-T细胞功能并克服肿瘤微环境障碍的策略

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-025-06606-z

Park, Brandon; Kim, Joshua; Baylink, David J; Hino, Christopher; Kwon, Cedric; Tran, Victoria; Xiao, Jeffrey; Cao, Huynh; Lee, Scott; Tan, Laren; Chang, Andrew; Saca, Luis; Matus, Michael; Lobo Moreno, Pamela; Schill-Depew, Amy; Abdel-Azim, Hisham; Mirshahidi, Hamid; Xu, Yi

Navigating contradictions in enteric chemotactic stimuli

应对肠道趋化刺激中的矛盾

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.106261

Franco, Kailie; Gentry-Lear, Zealon; Shavlik, Michael; Harms, Michael J; Baylink, Arden

发表日期：2025

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Assessment of Feasibility of the M2 Macrophage-Based Adoptive Gene Transfer Strategy for Osteoarthritis with a Mouse Model

利用小鼠模型评估基于M2巨噬细胞的过继基因转移策略治疗骨关节炎的可行性

期刊:Cells

影响因子:5.2

doi:10.3390/cells14141067

Sheng, Matilda H-C; Baylink, David J; Rundle, Charles H; Lau, Kin-Hing William

HilD-regulated chemotaxis proteins contribute to Salmonella Typhimurium colonization in the gut

HilD调控的趋化蛋白促进鼠伤寒沙门氏菌在肠道的定植。

期刊:mBio

影响因子:4.7

doi:10.1128/mbio.00390-25

Cooper, Kendal G; Kari, Laszlo; Chong, Audrey; Tandon, Naman; Doran, Kathleen; Gomes Da Silva, Lidiane; Cockrell, Diane C; Baylink, Arden; Steele-Mortimer, Olivia

Conditional Deletion of Gremlin-1 in Cathepsin K-expressing Mature Osteoclasts Altered the Skeletal Response to Calcium Depletion in Sex-Dependent Manner

在表达组织蛋白酶K的成熟破骨细胞中条件性敲除Gremlin-1，以性别依赖的方式改变了骨骼对钙耗竭的反应。

期刊:Calcified Tissue International

影响因子:3.2

doi:10.1007/s00223-024-01337-7

Sheng, Matilda H-C; Rundle, Charles H; Baylink, David J; Lau, Kin-Hing William

细胞生物学

发表日期：2025

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Bacterial vampirism mediated through taxis to serum

通过血清趋化作用介导的细菌吸血

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.93178

Siena J Glenn #, Zealon Gentry-Lear #, Michael Shavlik, Michael J Harms, Thomas J Asaki, Arden Baylink

微生物学

发表日期：2024

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Structure and signaling mechanism of Helicobacter pylori transducer-like protein D

幽门螺杆菌转导样蛋白D的结构和信号传导机制

Exploring treatment-driven subclonal evolution of prognostic triple biomarkers: Dual gene fusions and chimeric RNA variants in novel subtypes of acute myeloid leukemia patients with KMT2A rearrangement

探索治疗驱动的预后三重生物标志物的亚克隆演变：KMT2A重排急性髓系白血病患者新亚型中的双基因融合和嵌合RNA变体

Targeting DNA helicase CMG complex and NFκB2-driven drug-resistant transcriptional axis to effectively treat KRAS(G12D)-mutated pancreatic cancer

靶向DNA解旋酶CMG复合物和NFκB2驱动的耐药转录轴，以有效治疗KRAS(G12D)突变型胰腺癌

Author Correction: Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage

作者更正：利用 CRISPR/Cas9 介导的双链 DNA 切割，通过双切割 HDR 供体实现高效精确的基因敲入

Nutrient-gene therapy as a strategy to enhance CAR T cell function and overcome barriers in the tumor microenvironment

营养基因疗法作为一种增强CAR-T细胞功能并克服肿瘤微环境障碍的策略

Navigating contradictions in enteric chemotactic stimuli

应对肠道趋化刺激中的矛盾

Assessment of Feasibility of the M2 Macrophage-Based Adoptive Gene Transfer Strategy for Osteoarthritis with a Mouse Model

利用小鼠模型评估基于M2巨噬细胞的过继基因转移策略治疗骨关节炎的可行性

HilD-regulated chemotaxis proteins contribute to Salmonella Typhimurium colonization in the gut

HilD调控的趋化蛋白促进鼠伤寒沙门氏菌在肠道的定植。

Conditional Deletion of Gremlin-1 in Cathepsin K-expressing Mature Osteoclasts Altered the Skeletal Response to Calcium Depletion in Sex-Dependent Manner

在表达组织蛋白酶K的成熟破骨细胞中条件性敲除Gremlin-1，以性别依赖的方式改变了骨骼对钙耗竭的反应。

Bacterial vampirism mediated through taxis to serum

通过血清趋化作用介导的细菌吸血