日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Antifungal Structure-Activity Relationship Studies of Broad-Spectrum Phenothiazines

广谱吩噻嗪类抗真菌药物的构效关系研究

Brosend, Samantha C; Guin, Soumitra; Giovine, Gregory; Gadalla, Carlos; Campos, Miguel A; Mara, Alisa; Jentsch, Nicholas G; Thakellapalli, Haresh; Alden, Kathryn M; Beattie, Sarah R; Krysan, Damian J; Meyers, Marvin J

CWHM-974 is a fluphenazine derivative with improved antifungal activity against Candida albicans due to reduced susceptibility to multidrug transporter-mediated resistance mechanisms

CWHM-974 是一种氟奋乃静衍生物,由于其对多药转运蛋白介导的耐药机制的敏感性降低,因此对白色念珠菌具有更强的抗真菌活性。

Miron-Ocampo, Aracely; Beattie, Sarah R; Guin, Soumitra; Conway, Thomas; Meyers, Marvin J; Moye-Rowley, W Scott; Krysan, Damian J

Novel Keto-Alkyl-Pyridinium Antifungal Molecules Active in Models of In Vivo Candida albicans Vascular Catheter Infection and Ex Vivo Candida auris Skin Colonization.

新型酮烷基吡啶类抗真菌分子在体内白色念珠菌血管导管感染和体外耳念珠菌皮肤定植模型中具有活性

Beattie Sarah R, Esan Taiwo, Zarnowski Robert, Eix Emily, Nett Jeniel E, Andes David R, Hagen Timothy, Krysan Damian J

Novel keto-alkyl-pyridinium antifungal molecules active in models of in vivo Candida albicans vascular catheter infection and ex vivo Candida auris skin colonization.

新型酮烷基吡啶类抗真菌分子在体内白色念珠菌血管导管感染模型和体外耳念珠菌皮肤定植模型中均表现出活性

Beattie Sarah R, Esan Taiwo, Zarnowski Robert, Eix Emily, Nett Jeniel E, Andes David R, Hagen Timothy, Krysan Damian J

Gluconate Kinase Is Required for Gluconate Assimilation and Sporulation in Cryptococcus neoformans.

葡萄糖酸激酶是新型隐球菌葡萄糖酸同化和孢子形成所必需的

Jezewski Andrew J, Beattie Sarah R, Alden Katy M, Krysan Damian J

Enantioselective Synthesis of (+)-Hippolide J and Reevaluation of Antifungal Activity

(+)-Hippolide J 的对映选择性合成及其抗真菌活性的重新评价

Guo, Renyu; Beattie, Sarah R; Krysan, Damian J; Brown, M Kevin

Characterizing the Pathogenic, Genomic, and Chemical Traits of Aspergillus fischeri, a Close Relative of the Major Human Fungal Pathogen Aspergillus fumigatus.

对费氏曲霉(Aspergillus fischeri)的致病性、基因组和化学特性进行表征,费氏曲霉是人类主要真菌病原体烟曲霉(Aspergillus fumigatus)的近亲

Mead Matthew E, Knowles Sonja L, Raja Huzefa A, Beattie Sarah R, Kowalski Caitlin H, Steenwyk Jacob L, Silva Lilian P, Chiaratto Jessica, Ries Laure N A, Goldman Gustavo H, Cramer Robert A, Oberlies Nicholas H, Rokas Antonis

Response to Comment on "Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death"

对“肺部杀菌免疫依赖于靶向真菌凋亡样程序性细胞死亡”一文的评论的回应

Shlezinger, Neta; Irmer, Henriette; Dhingra, Sourabh; Beattie, Sarah R; Cramer, Robert A; Braus, Gerhard H; Sharon, Amir; Hohl, Tobias M

Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death

肺部的杀菌免疫依赖于靶向真菌凋亡样程序性细胞死亡

Shlezinger, Neta; Irmer, Henriette; Dhingra, Sourabh; Beattie, Sarah R; Cramer, Robert A; Braus, Gerhard H; Sharon, Amir; Hohl, Tobias M

Filamentous fungal carbon catabolite repression supports metabolic plasticity and stress responses essential for disease progression

丝状真菌碳代谢物阻遏作用支持代谢可塑性和应激反应,这对疾病进展至关重要。

Beattie, Sarah R; Mark, Kenneth M K; Thammahong, Arsa; Ries, Laure Nicolas Annick; Dhingra, Sourabh; Caffrey-Carr, Alayna K; Cheng, Chao; Black, Candice C; Bowyer, Paul; Bromley, Michael J; Obar, Joshua J; Goldman, Gustavo H; Cramer, Robert A