日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Receptor-Mediated Shuttling of a D-Amino Acid Peptide Achieves High Nanomolar Cytosolic Concentrations

受体介导的D-氨基酸肽转运可实现胞质内高纳摩尔浓度

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c12876
List, Moritz; Beck-Sickinger, Annette G
信号转导
发表日期：2026
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The pathway-independent positive allosteric modulator C1 allows for the identification of active Y(4) receptor relevant positions

通路非依赖性正向变构调节剂C1可用于识别活性Y(4)受体的相关位点。

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-025-06019-7
Schüß, Corinna; Vu, Oanh; Pelczyk, Tim; Schubert, Mario; Du, Yu; Stichel, Jan; Weaver, C David; Meiler, Jens; Beck-Sickinger, Annette G
信号转导
发表日期：2026
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Modulating food intake by nasal application of peptides targeting melanocortin 4 receptor and ghrelin receptor systems

通过鼻腔施用靶向黑皮质素4受体和胃饥饿素受体系统的肽来调节食物摄入量

期刊:Brain Communications
影响因子:4.5
doi:10.1093/braincomms/fcaf450
Özbay, Benginur; Jülke, Eva-Maria; List, Moritz; Nowicki, Marcin; Els-Heindl, Sylvia; Immig, Kerstin; Mörl, Karin; Bechmann, Ingo; Beck-Sickinger, Annette G
信号转导
发表日期：2026
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Transient ligand contacts of the intrinsically disordered N-terminus of neuropeptide Y(2) receptor regulate arrestin-3 recruitment

神经肽Y(2)受体固有无序N端的瞬时配体接触调节arrestin-3的募集

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-64051-4
Kaiser, Anette; Rojas Echeverri, Juan C; Baischew, Asat; Pankonin, Maik; Leitner, Karl D; Iacobucci, Claudio; Sala, Davide; Ihling, Christian; Müller, Ronny; Ferenc, Rok; Beck-Sickinger, Annette G; Schmidt, Peter; Meiler, Jens; Hildebrand, Peter W; Sinz, Andrea
信号转导
发表日期：2025
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MRAP2 modifies the signaling and oligomerization state of the melanocortin-4 receptor.

MRAP2 改变黑皮质素-4 受体的信号传导和寡聚化状态

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-63988-w
Sohail Iqra, Laurin Suli-Anne, Kleinau Gunnar, Chunilal Vidicha, Morton Andrew, Brenlla Alfonso, Kagiali Zeynep Cansu Uretmen, Blouin Marie-José, Tello Javier A, Beck-Sickinger Annette G, Lohse Martin J, Scheerer Patrick, Bouvier Michel, McCormick Peter, Annibale Paolo, Biebermann Heike
信号转导
发表日期：2025
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Similar Binding Mode of a 5-Sulfonylthiouracil Derivative Antagonist at Chemerin Receptors CMKLR1 and GPR1

5-磺酰硫脲嘧啶衍生物拮抗剂与趋化素受体CMKLR1和GPR1的结合模式相似

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00135
Schermeng, Tina; Fürll, Alexander; Liessmann, Fabian; von Bredow, Lukas; Stichel, Jan; Weaver, C David; Tretbar, Maik; Meiler, Jens; Beck-Sickinger, Annette G
信号转导
发表日期：2025
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Dual Targeting Approach Using 4-Hydroxytamoxifen Neuropeptide Y Conjugates for Selective Addressing of Adipose Tissue

利用4-羟基他莫昔芬神经肽Y缀合物选择性靶向脂肪组织的双重靶向策略

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.202500668
Kohler, Anna; Jülke, Eva-Maria; Darveniza, Luke C; Stichel, Jan; Beck-Sickinger, Annette G
发表日期：2025
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Development of Mutant M(3) Muscarinic Receptors Biased for G Protein Activation or Recruitment of β-Arrestins

突变型M(3)毒蕈碱受体的发育使其偏向于G蛋白激活或β-抑制蛋白的募集。

期刊:Biochemistry
影响因子:3
doi:10.1021/acs.biochem.5c00036
Meister, Jaroslawna; Wanka, Lizzy; Perry-Hauser, Nicole A; Liu, Liu; Iverson, Tina M; Gurevich, Vsevolod V; Beck-Sickinger, Annette G; Kruse, Andrew C; Wess, Jürgen
信号转导
发育与干细胞
发表日期：2025
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Development of a Potent and Selective G2A (GPR132) Agonist.

开发一种高效选择性的G2A（GPR132）激动剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.3c02164
Hernandez-Olmos Victor, Heering Jan, Marinescu Beatrice, Schermeng Tina, Ivanov Vladimir V, Moroz Yurii S, Nevermann Sheila, Mathes Marius, Ehrler Johanna H M, Alnouri Mohamad Wessam, Wolf Markus, Haydo Alicia S, Schmachtel Tessa, Zaliani Andrea, Höfner Georg, Kaiser Astrid, Schubert-Zsilavecz Manfred, Beck-Sickinger Annette G, Offermanns Stefan, Gribbon Philipp, Rieger Michael A, Merk Daniel, Sisignano Marco, Steinhilber Dieter, Proschak Ewgenij
发表日期：2024
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Comparison of Protocols to Test Peptide Stability in Blood Plasma and Cell Culture Supernatants

比较检测血浆和细胞培养上清液中肽稳定性的方案

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.4c00503
Kohler, Anna; Jülke, Eva-Maria; Stichel, Jan; Beck-Sickinger, Annette G
Cell Culture
细胞生物学
发表日期：2024
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