日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mithramycin alters EWS::FLI1 DNA binding and RNA polymerase II processivity to inhibit nascent transcription

米索霉素通过改变 EWS::FLI1 与 DNA 的结合以及 RNA 聚合酶 II 的加工能力来抑制新生转录。

Kaufman, Rebecca; Flores, Guillermo; Boguslawski, Elissa A; Kinn-Gurzo, Seneca; Chassé, Maggie; Beddows, Ian; Adams, Marie; Stout, Matthew C; Gaetano, Lauren; Lopez, Raphael; Veluvolu, Sridhar; Fuller, Andrew; Kitchen-Goosen, Susan M; Tolstyka, Zachary P; Gedminas, Jenna M; Grohar, Patrick J

A novel humanized immune stroma PDX cancer model for therapeutic studies

一种用于治疗研究的新型人源化免疫基质PDX癌症模型

Yang, Dongli; Beddows, Ian; Tang, Huijuan; Bai, Shoumei; Cascio, Sandra; McGonigal, Stacy C; Johnson, Benjamin K; Powers, John J; Acharya, Rajesh; Bao, Riyue; Bruno, Tullia C; Soong, T Rinda; Conejo-Garcia, Jose R; Shen, Hui; Bility, Moses T; Buckanovich, Ronald J

Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation.

衰老和携带 BRCA 突变的基质细胞驱动上皮细胞转化

Garcia Geyon L, Orellana Taylor, Gorecki Grace, Frisbie Leonard, Baruwal Roja, Suresh Swathi, Goldfeld Ester, Beddows Ian, MacFawn Ian P, Britt Ananya K, Hale Macy M, Elhaw Amal Taher, Isett Brian R, Hempel Nadine, Bao Riyue, Shen Hui, Buckanovich Ronald J, Finkel Toren, Drapkin Ronny, Soong T Rinda, Bruno Tullia C, Atiya Huda I, Coffman Lan G

Impact of BRCA mutations, age, surgical indication, and hormone status on the molecular phenotype of the human Fallopian tube

BRCA基因突变、年龄、手术指征和激素水平对人类输卵管分子表型的影响

Beddows, Ian; Djirackor, Svetlana; Omran, Dalia K; Jung, Euihye; Shih, Natalie Nc; Roy, Ritu; Hechmer, Aaron; Olshen, Adam; Adelmant, Guillaume; Tom, Ann; Morrison, Jacob; Adams, Marie; Rohrer, Daniel C; Schwartz, Lauren E; Pearce, Celeste Leigh; Auman, Heidi; Marto, Jarrod A; Drescher, Charles W; Drapkin, Ronny; Shen, Hui

Tranquillyzer: A Flexible Neural Network Framework for Structural Annotation and Demultiplexing of Long-Read Transcriptomes

Tranquillyzer:一种用于长读长转录组结构注释和解复用的灵活神经网络框架

Semwal, Ayush; Morrison, Jacob; Beddows, Ian; Palmer, Theron; Majewski, Mary F; Jang, H Josh; Johnson, Benjamin K; Shen, Hui

BISCUIT: an efficient, standards-compliant tool suite for simultaneous genetic and epigenetic inference in bulk and single-cell studies

BISCUIT:一套高效、符合标准的工具套件,用于在批量和单细胞研究中同时进行遗传和表观遗传推断。

Zhou, Wanding; Johnson, Benjamin K; Morrison, Jacob; Beddows, Ian; Eapen, James; Katsman, Efrat; Semwal, Ayush; Habib, Walid Abi; Heo, Lyong; Laird, Peter W; Berman, Benjamin P; Triche, Timothy J Jr; Shen, Hui

A Novel Humanized Immune Stroma PDX Cancer Model for Therapeutic Studies

一种用于治疗研究的新型人源化免疫基质PDX癌症模型

Yang, Dongli; Beddows, Ian; Tang, Huijuan; Cascio, Sandra; McGonigal, Stacy C; Bai, Shoumei; Johnson, Benjamin K; Powers, John J; Acharya, Rajesh; Bao, Riyue; Bruno, Tullia C; Soong, Thing R; Conejo-Garcia, Jose R; Shen, Hui; Bility, Moses T; Buckanovich, Ronald J

PGC-1β maintains mitochondrial metabolism and restrains inflammatory gene expression

PGC-1β维持线粒体代谢并抑制炎症基因表达

Guak, Hannah; Sheldon, Ryan D; Beddows, Ian; Vander Ark, Alexandra; Weiland, Matthew J; Shen, Hui; Jones, Russell G; St-Pierre, Julie; Ma, Eric H; Krawczyk, Connie M

Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson's Disease

肠道菌群失调与帕金森病患者胆汁酸水平升高有关

Li, Peipei; Killinger, Bryan A; Ensink, Elizabeth; Beddows, Ian; Yilmaz, Ali; Lubben, Noah; Lamp, Jared; Schilthuis, Meghan; Vega, Irving E; Woltjer, Randy; Pospisilik, J Andrew; Brundin, Patrik; Brundin, Lena; Graham, Stewart F; Labrie, Viviane

Examining the molecular mechanisms contributing to the success of an invasive species across different ecosystems

研究入侵物种在不同生态系统中成功生存的分子机制

Lamar, Sarah K; Beddows, Ian; Partridge, Charlyn G