日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The oncogenic control of nucleotide synthesis

核苷酸合成的致癌控制

Vidal-Cruchez, Olivia; Ben-Sahra, Issam

MLL3/4 methyltransferases regulate the differentiation of pluripotent stem cells through coordinating glycolysis and mitochondrial respiration

MLL3/4甲基转移酶通过协调糖酵解和线粒体呼吸作用来调节多能干细胞的分化。

Nur, Suza Mohammad; Jia, Yunbo; Ye, Muyi; Lepak, Caylin A; Ben-Sahra, Issam; Cao, Kaixiang

Mechano-dependent sorbitol accumulation supports biomolecular condensate.

机械依赖性山梨醇积累支持生物分子凝聚体

Torrino Stephanie, Oldham William M, Tejedor Andrés R, Burgos Ignacio S, Nasr Lara, Rachedi Nesrine, Fraissard Kéren, Chauvet Caroline, Sbai Chaima, O'Hara Brendan P, Abélanet Sophie, Brau Frederic, Favard Cyril, Clavel Stephan, Collepardo-Guevara Rosana, Espinosa Jorge R, Ben-Sahra Issam, Bertero Thomas

De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma.

从头合成丝氨酸是一种代谢弱点,可以利用这种弱点来克服晚期肾细胞癌的舒尼替尼耐药性

Teisseire Manon, Sahu Umakant, Parola Julien, Tsai Meng-Chen, Vial Valérie, Durivault Jérôme, Grépin Renaud, Cormerais Yann, Molina Clément, Gouraud Arthur, Pagès Gilles, Ben-Sahra Issam, Giuliano Sandy

Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cycle

琥珀酸的积累通过琥珀酰化介导的线粒体叶酸循环调控抑制嘌呤的从头合成。

Mushtaq A Nengroo ,Austin T Klein ,Heather S Carr ,Olivia Vidal-Cruchez ,Umakant Sahu ,Daniel J McGrail ,Nidhi Sahni ,Niklas B Thompson ,Peter A Faull ,Peng Gao ,John M Asara ,Hardik Shah ,Marc L Mendillo ,Issam Ben-Sahra

Purifying and profiling lysosomes to expand understanding of lysosomal dysfunction-associated diseases

纯化和分析溶酶体以加深对溶酶体功能障碍相关疾病的理解

Shilatifard, Ali; Ben-Sahra, Issam

The extracellular matrix drives guanylate production and protects pancreatic cancer cells from oxaliplatin-induced DNA damage

细胞外基质驱动鸟苷酸生成,并保护胰腺癌细胞免受奥沙利铂诱导的DNA损伤。

Efthymiou, Georgios; Lohmann, Eugénie; Montenegro, Claudio; Kousteridou, Paraskevi; Bertrand, Pierre; Pereira, Julia; Carr, Heather S; Ben-Sahra, Issam; Compare, Coralie; Nemazanyy, Ivan; Bidaut, Ghislain; Finetti, Pascal; Bertucci, François; Lachaud, Christophe; Guillaumond, Fabienne; Tomasini, Richard; Vasseur, Sophie

Control of circadian muscle glucose metabolism through the BMAL1-HIF axis in obesity.

肥胖症中通过 BMAL1-HIF 轴控制昼夜节律肌肉葡萄糖代谢

Chaikin Claire A, Thakkar Abhishek V, Steffeck Adam W T, Pfrender Eric M, Hung Kaitlyn, Zhu Pei, Waldeck Nathan J, Nozawa Rino, Song Weimin, Futtner Christopher R, Quattrocelli Mattia, Bass Joseph, Ben-Sahra Issam, Peek Clara B

Succinate dehydrogenase activity supports de novo purine synthesis.

琥珀酸脱氢酶活性支持嘌呤的从头合成

Nengroo Mushtaq A, Klein Austin T, Carr Heather S, Vidal-Cruchez Olivia, Sahu Umakant, McGrail Daniel J, Sahni Nidhi, Gao Peng, Asara John M, Shah Hardik, Mendillo Marc L, Ben-Sahra Issam

Parallel multiOMIC analysis reveals glutamine deprivation enhances directed differentiation of renal organoids.

平行多组学分析表明,谷氨酰胺缺乏可增强肾脏类器官的定向分化

Sarami Iman, Hekman Katherine E, Gupta Ashwani Kumar, Snider Justin M, Ivancic David, Zec Manja, Kandpal Manoj, Ben-Sahra Issam, Menon Rajasree, Otto Edgar A, Chilton Floyd H, Wertheim Jason A