日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment

对放射免疫疗法的不同反应是由肿瘤微环境的内在特征决定的。

Gadwa, Jacob; Yu, Justin; Piper, Miles; Knitz, Michael W; Darragh, Laurel B; Olimpo, Nicholas; Corbo, Sophia; Beynor, Jessica I; Neupert, Brooke; Nguyen, Alexander T; Hodgson, Chloe; Nguyen, Diemmy; Abdelazeem, Khalid Nm; Saviola, Anthony; Pousse, Laurene; Bransi, Ali; Pincha, Mudita; Klein, Christian; Amann, Maria; Karam, Sana D

PPARα Agonism Enhances Immune Response to Radiotherapy While Dietary Oleic Acid Results in Counteraction

PPARα激动剂可增强放射疗法的免疫反应,而膳食油酸则会产生拮抗作用。

Richard Blake Ross ,Jacob Gadwa ,Justin Yu ,Laurel B Darragh ,Michael W Knitz ,Diemmy Nguyen ,Nicholas A Olimpo ,Khalid N M Abdelazeem ,Alexander Nguyen ,Sophia Corbo ,Benjamin Van Court ,Jessica Beynor ,Brooke Neupert ,Anthony J Saviola ,Angelo D'Alessandro ,Sana D Karam

IL7 in combination with radiotherapy stimulates a memory T-cell response to improve outcomes in HNSCC models

IL7 与放射疗法联合使用可刺激记忆 T 细胞反应,从而改善 HNSCC 模型的预后

Justin Yu, Jacob Gadwa, Richard B Ross, Michael Knitz, Laurel B Darragh, Khalid N M Abdelazeem, Jessica Beynor, Brooke Neupert, Alexander Nguyen, Diemmy Nguyen, Nicholas Olimpo, Sophia Corbo, Benjamin Van Court, Angelo D'Alessandro, Anthony Saviola, Sana D Karam

Single-cell eQTL models reveal dynamic T cell state dependence of disease loci

单细胞eQTL模型揭示疾病位点对T细胞状态的动态依赖性

Nathan, Aparna; Asgari, Samira; Ishigaki, Kazuyoshi; Valencia, Cristian; Amariuta, Tiffany; Luo, Yang; Beynor, Jessica I; Baglaenko, Yuriy; Suliman, Sara; Price, Alkes L; Lecca, Leonid; Murray, Megan B; Moody, D Branch; Raychaudhuri, Soumya

Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease

通过多模态分析结核病患者群体中的记忆 T 细胞,可以确定细胞状态与人口统计、环境和疾病之间的关联

Aparna Nathan, Jessica I Beynor, Yuriy Baglaenko, Sara Suliman, Kazuyoshi Ishigaki, Samira Asgari, Chuan-Chin Huang, Yang Luo, Zibiao Zhang, Kattya Lopez, Cecilia S Lindestam Arlehamn, Joel D Ernst, Judith Jimenez, Roger I Calderón, Leonid Lecca, Ildiko Van Rhijn, D Branch Moody, Megan B Murray, Sou

IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation

IFN-γ 和 TNF-α 驱动 CXCL10+ CCL2+ 巨噬细胞表型扩增,这种表型在重症 COVID-19 肺部和伴有组织炎症的炎症性疾病中均有发现。

Fan Zhang ,Joseph R Mears ,Lorien Shakib ,Jessica I Beynor ,Sara Shanaj ,Ilya Korsunsky ,Aparna Nathan ,Soumya Raychaudhuri #

Multimodal single-cell approaches shed light on T cell heterogeneity

多模态单细胞方法揭示了T细胞的异质性

Nathan, Aparna; Baglaenko, Yuriy; Fonseka, Chamith Y; Beynor, Jessica I; Raychaudhuri, Soumya