日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Integrating binding affinity and tonic signaling enables a rational CAR design for augmented T cell function.

结合亲和力和持续信号传导可以实现合理的 CAR 设计，从而增强 T 细胞功能

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2024-010208
Barden Markus, Elsenbroich Patrick Ronan, Haas Vivian, Ertelt Moritz, Pervan Philip, Velas Lukas, Gergely Bence, Szöőr Árpád, Harrer Dennis Christoph, Bezler Valerie, Holzinger Astrid, Friis Rasmus Ulslev Wegener, Vereb Gyorgy, Schütz Gerhard J, Schoeder Clara T, Hombach Andreas A, Abken Hinrich
信号转导
细胞生物学
发表日期：2024
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Automated manufacturing and characterization of clinical grade autologous CD20 CAR T cells for the treatment of patients with stage III/IV melanoma

用于治疗 III/IV 期黑色素瘤患者的临床级自体 CD20 CAR T 细胞的自动化生产和表征

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2024.1328368
Aleksandrova, Krasimira; Leise, Jana; Priesner, Christoph; Aktas, Murat; Apel, Michael; Assenmacher, Mario; Bürger, Iris; Richter, Anne; Altefrohne, Pia; Schubert, Christine; Holzinger, Astrid; Barden, Markus; Bezler, Valerie; von Bergwelt-Baildon, Michael; Borchmann, Peter; Goudeva, Lilia; Glienke, Wolfgang; Arseniev, Lubomir; Esser, Ruth; Abken, Hinrich; Koehl, Ulrike
黑色素瘤
T细胞
CD20
细胞生物学
CD2
发表日期：2024
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IRF4 downregulation improves sensitivity and endurance of CAR T cell functional capacities

IRF4下调可提高CAR-T细胞功能能力的敏感性和持久性。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2023.1185618
Harrer, Dennis Christoph; Bezler, Valerie; Hartley, Jordan; Herr, Wolfgang; Abken, Hinrich
细胞生物学
T细胞
T细胞
免疫/内分泌
发表日期：2023
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Regional adaptation of the education in palliative and end-of-life Care Pediatrics (EPEC-Pediatrics) curriculum in Eurasia

欧亚地区姑息治疗和临终关怀儿科教育（EPEC-Pediatrics）课程的区域性调整

期刊:Cancer Medicine
影响因子:3.1
doi:10.1002/cam4.5213
McNeil, Michael J; Ehrlich, Bella; Yakimkova, Taisiya; Wang, Huiqi; Mishkova, Volha; Bezler, Zhanna; Kumirova, Ella; Madni, Arshia; Movsisyan, Narine; Williams, Karen; Baizakova, Baglan; Borisevich, Marina; Chatman, Georgia; Erimbetova, Indira; Quintero, Ximena Garcia; Golban, Rodica; Kirby, Brandi; Nunez, Paola; Ranadive, Radhikesh; Sakhar, Nadezhda; Sonnenfelt, Jason; Volkova, Alisa; Moreira, Daniel; Friedrichsdorf, Stefan J; Wolfe, Joanne; Remke, Stacy; Hauser, Joshua; Devidas, Meenakshi; Baker, Justin N; Agulnik, Asya
发表日期：2023
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CAR Triggered Release of Type-1 Interferon Limits CAR T-Cell Activities by an Artificial Negative Autocrine Loop

CAR触发的I型干扰素释放通过人工负向自分泌环路限制CAR T细胞活性

期刊:Cells
影响因子:5.2
doi:10.3390/cells11233839
Harrer, Dennis Christoph; Schenkel, Charlotte; Bezler, Valerie; Kaljanac, Marcell; Hartley, Jordan; Barden, Markus; Pan, Hong; Holzinger, Astrid; Herr, Wolfgang; Abken, Hinrich
细胞生物学
T细胞
T细胞
免疫/内分泌
发表日期：2022
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Atypical and distinct microtubule radial symmetries in the centriole and the axoneme of Lecudina tuzetae.

Lecudina tuzetae 的中心粒和轴丝中存在非典型和独特的微管放射状对称性

期刊:Molecular Biology of the Cell
影响因子:2.7
doi:10.1091/mbc.E22-04-0123
Bezler Alexandra, Woglar Alexander, Schneider Fabian, Douma Friso, Bürgy Léo, Busso Coralie, Gönczy Pierre
其它
发表日期：2022
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Novel features of centriole polarity and cartwheel stacking revealed by cryo-tomography

低温断层扫描揭示中心粒极性和车轮状堆积的新特征

期刊:EMBO Journal
影响因子:9.4
doi:10.15252/embj.2020106249
Sergey Nazarov #, Alexandra Bezler #, Georgios N Hatzopoulos #, Veronika Nemčíková Villímová, Davide Demurtas, Maeva Le Guennec, Paul Guichard, Pierre Gönczy
发表日期：2020
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Designed Ankyrin Repeat Protein (DARPin) to target chimeric antigen receptor (CAR)-redirected T cells towards CD4+ T cells to reduce the latent HIV+ cell reservoir

设计锚蛋白重复蛋白 (DARPin)，将嵌合抗原受体 (CAR) 重定向的 T 细胞靶向 CD4+ T 细胞，以减少潜伏的 HIV+ 细胞库

期刊:Medical Microbiology and Immunology
影响因子:5.5
doi:10.1007/s00430-020-00692-0
Lea Patasic, Janna Seifried, Valerie Bezler, Marcell Kaljanac, Irene C Schneider, Heike Schmitz, Christiane Tondera, Jessica Hartmann, Andreas Hombach, Christian J Buchholz, Hinrich Abken, Renate König, Klaus Cichutek1
免疫
细胞生物学
T细胞
T Cell Receptor
AROS
发表日期：2020
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Frontline Science: Escherichia coli use LPS as decoy to impair neutrophil chemotaxis and defeat antimicrobial host defense

前沿科学：大肠杆菌利用 LPS 作为诱饵来削弱中性粒细胞趋化性并击败抗菌宿主防御

期刊:Journal of Leukocyte Biology
影响因子:3.6
doi:10.1002/JLB.4HI0319-109R
Yutaka Kondo, Carola Ledderose, Christian J Slubowski, Mahtab Fakhari, Yuka Sumi, Koichiro Sueyoshi, Ann-Katrin Bezler, Dilan Aytan, Mona Arbab, Wolfgang G Junger
免疫
细胞生物学
粒细胞
发表日期：2019
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Tissue- and sex-specific small RNAomes reveal sex differences in response to the environment

组织和性别特异性小RNA组揭示了性别对环境反应的差异

期刊:PLoS Genetics
影响因子:
doi:10.1371/journal.pgen.1007905
Alexandra Bezler, Fabian Braukmann, Sean M West, Arthur Duplan, Raffaella Conconi, Frédéric Schütz, Pierre Gönczy, Fabio Piano, Kristin Gunsalus, Eric A Miska, Laurent Keller
发表日期：2019
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