日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Volumetric compression regulates the phase separation of AXIN and acts as an operational amplifier to bidirectionally modulate Wnt signaling in organoids

体积压缩调节AXIN的相位分离，并作为运算放大器双向调节类器官中的Wnt信号传导。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-68209-y
Shi, Jinyun; Wu, Linze; Li, Pengjie; Qi, Fukang; Lei, Mengcheng; Ren, Xueqing; Xie, Han; Wang, Wenhui; Zheng, Yi; Chen, Peng; Xia, Limin; Shi, Chen; Zhang, Yu; Liu, Bi-Feng; Li, Yiwei
3D/类器官
信号转导
Wnt/β-Catenin
发表日期：2026
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Safety and preliminary efficacy results of IBI389, an anti-Claudin18.2×CD3 bispecific antibody, in patients with solid tumors and gastric or gastro-esophageal tumors: a phase 1 dose escalation and expansion study

IBI389（一种抗Claudin18.2×CD3双特异性抗体）在实体瘤和胃或胃食管肿瘤患者中的安全性和初步疗效结果：一项1期剂量递增和扩展研究

期刊:BMC Medicine
影响因子:8.3
doi:10.1186/s12916-025-04597-8
Li, Xiaoyu; Dai, Ruihong; Xu, Qi; Guo, Zengqing; Hu, Changlu; Sun, Yuping; Niu, Zuoxing; Hao, Jihui; Zhang, Mingjun; Dai, Guanghai; Hua, Dong; Pan, Yueyin; Wang, Xin; Wei, Shuqing; Chen, Xiaobing; Wu, Qian; Zhang, Yulong; Zhou, Hui; Ying, Jieer; Zheng, Li; Bi, Feng
CD3
肿瘤
肿瘤免疫
发表日期：2026
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CapeOX (capecitabine and oxaliplatin) combined with sintilimab and bevacizumab biosimilar (IBI305) for first-line treatment of advanced gastric or oesophagogastric junction adenocarcinoma: study protocol for a single-arm, phase Ib/II trial

CapeOX（卡培他滨和奥沙利铂）联合信迪利单抗和贝伐单抗生物类似药（IBI305）一线治疗晚期胃癌或食管胃交界处腺癌：一项单臂Ib/II期试验的研究方案

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2024-086005
Dai, Ruihong; Zhang, Pengfei; Cheng, Mo; Bi, Feng; Zhou, Jitao; Liu, Ming
胃癌
肿瘤
肿瘤免疫
发表日期：2026
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The claudin-18.2-CD3 bispecific antibody IBI389 exerts an antitumor effect on malignant tumors with positive claudin-18.2 expression by promoting T-cell infiltration and remodeling the tumor immune microenvironment

Claudin-18.2-CD3双特异性抗体IBI389通过促进T细胞浸润和重塑肿瘤免疫微环境，对Claudin-18.2表达阳性的恶性肿瘤发挥抗肿瘤作用。

期刊:Translational Cancer Research
影响因子:1.7
doi:10.21037/tcr-2026-0474
Zhu, Yajie; Liu, Xiaorong; Zhang, Chenliang; Zhou, Shuang; Ye, Di; Tang, Qiulin; Xiao, Hengyi; Bi, Feng
肿瘤
T细胞
肿瘤免疫
Claudin-1
CD3
T细胞
细胞生物学
免疫/内分泌
发表日期：2026
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Synergizing Nanosensor-Enhanced Wearable Devices with Machine Learning for Precision Health Management Benefiting Older Adult Populations

将纳米传感器增强型可穿戴设备与机器学习相结合，实现精准健康管理，造福老年人群体

期刊:ACS Nano
影响因子:16
doi:10.1021/acsnano.5c04337
Li, Zhihao; He, Bangshun; Li, Yiwei; Liu, Bi-Feng; Zhang, Guojun; Liu, Songlin; Hu, Tony Ye; Li, Ying
发表日期：2025
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Engineering triple O-Ti-O vacancy associates for efficient water-activation catalysis

构建三重 O-Ti-O 空位缔合物以实现高效水活化催化

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-56190-5
Bi, Feng; Meng, Qingjie; Zhang, Yili; Chen, Hao; Jiang, Boqiong; Lu, Hanfeng; Liu, Qinghua; Zhang, Hongjun; Wu, Zhongbiao; Weng, Xiaole
发表日期：2025
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Identification of a Biomarker Panel in Extracellular Vesicles Derived From Non-Small Cell Lung Cancer (NSCLC) Through Proteomic Analysis and Machine Learning

通过蛋白质组学分析和机器学习鉴定非小细胞肺癌（NSCLC）来源的细胞外囊泡中的生物标志物组合

期刊:Journal of Extracellular Vesicles
影响因子:15.5
doi:10.1002/jev2.70078
Ye Yuan ，Hai Jiang ，Rui Xue ，Xiao-Jun Feng ，Bi-Feng Liu ，Lian Li ，Bo Peng ，Chen-Shuo Ren ，Shi-Min Li ，Na Li ，Min Li ，Dian-Bing Wang ，Xian-En Zhang
肺癌
细胞生物学
肿瘤
囊泡
肿瘤免疫
CLC
发表日期：2025
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Data-Driven Theoretical Modeling of Centrifugal Step Emulsification and Its Application in Comprehensive Multiscale Analysis

基于数据驱动的离心阶梯乳化理论建模及其在综合多尺度分析中的应用

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202411459
Wang, Xin; Cai, Xiaolu; Wan, Chao; Yuan, Huijuan; Li, Shunji; Zhang, Yiwei; Zhao, Ran; Qin, Yuxi; Li, Yiwei; Liu, Bi-Feng; Chen, Peng
发表日期：2025
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Editorial expression of concern: ERRα suppression enhances the cytotoxicity of the MEK inhibitor trametinib against colon cancer cells

编辑部关注：ERRα抑制增强MEK抑制剂曲美替尼对结肠癌细胞的细胞毒性

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-025-03507-3
Zhou, Sheng; Xia, Hongwei; Xu, Huanji; Tang, Qiulin; Nie, Yongzhan; Gong, Qi Yong; Bi, Feng
肿瘤
肠癌
肿瘤免疫
细胞生物学
毒理研究
发表日期：2025
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Integrated multi-omics analysis revealed that SMARCAL1 serves as an immune related prognostic marker and promotes liver cancer growth via the Hippo/YAP signaling axis

整合多组学分析表明，SMARCAL1作为一种免疫相关预后标志物，可通过Hippo/YAP信号通路促进肝癌生长。

期刊:International Journal of Surgery
影响因子:10.1
doi:10.1097/JS9.0000000000004567
Huang, Tingting; Tang, Meng; Tang, Qiulin; Di, Ye; Wang, Jiayu; Duan, Yichun; Zhang, Chenliang; Bi, Feng
肿瘤
肿瘤免疫
信号转导
SMARCAL1
YAP
肝癌
ARC
Hippo
免疫/内分泌
发表日期：2025
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